Stress and circulating cell-free mitochondrial DNA: a systematic review of human studies, physiological considerations, and technical recommendations
Cell-free mitochondrial DNA (cf-mtDNA) is a marker of inflammatory illness and a predictor of mortality, however little is thought about cf-mtDNA in relation to psychobiology. A scientific evaluation of the literature reveals that blood cf-mtDNA varies in relation to frequent real-world stressors together with psychopathology, acute psychological stress, and train. Furthermore, cf-mtDNA is inducible inside minutes and reveals excessive intra-individual day-to-day variation, highlighting the dynamic regulation of cf-mtDNA ranges.
We talk about present information on the mechanisms of cf-mtDNA launch, its types of transport (“cell-free” doesn’t imply “membrane-free”), potential physiological capabilities, putative mobile and neuroendocrine triggers, and elements which will contribute to cf-mtDNA removing from the circulation. A evaluation of in vitro, pre-clinical, and medical research exhibits conflicting outcomes across the dogma that physiological types of cf-mtDNA are pro-inflammatory, opening the opportunity of different physiological capabilities, together with the cell-to-cell switch of entire mitochondria.
Lastly, to boost the reproducibility and organic interpretation of human cf-mtDNA analysis, we suggest pointers for blood assortment, cf-mtDNA isolation, quantification, and reporting requirements, which might promote concerted advances by the group. Defining the mechanistic foundation for cf-mtDNA signaling is a chance to elucidate the position of mitochondria in brain-body interactions and psychopathology.
Evolution, systematics, and the unnatural historical past of mitochondrial DNA
The tenets underlying using mtDNA in phylogenetic and systematic analyses are strict maternal inheritance, clonality, homoplasmy, and distinction as a consequence of mutation: that’s, there are species-specific mtDNA sequences and phylogenetic reconstruction is a matter of evaluating these sequences and inferring closeness of relatedness from the diploma of sequence similarity. But, how mtDNA habits turned so outlined is mysterious.
Though early research of fertilization demonstrated for many animals that not solely the top, however the sperm’s tail and mitochondria-bearing midpiece penetrate the egg, the other – solely the top enters the egg – turned truth, and mtDNA conceived as maternally transmitted.
When midpiece/tail penetration was realized as true, the conceptions ‘strict maternal inheritance’, and so on., and their software to evolutionary endeavors, didn’t change. But there’s mounting proof of paternal mtDNA transmission, paternal and maternal mixture, intracellular recombination, and intra- and intercellular heteroplasmy. Clearly, these phenomena influence the systematic and phylogenetic evaluation of mtDNA sequences.
Mitochondrial DNA Evaluation Clarifies Taxonomic Standing of the Northernmost Snow Sheep ( Ovis nivicola) Inhabitants
At present, the intraspecific taxonomy of snow sheep (Ovis nivicola) is controversial and must be specified utilizing DNA molecular genetic markers. In our earlier work utilizing whole-genome single nucleotide polymorphism (SNP) evaluation, we discovered that the inhabitants inhabiting Kharaulakh Ridge was genetically totally different from the opposite populations of Yakut subspecies to which it was normally referred. Right here, our research was aimed on the clarification of taxonomic standing of Kharaulakh snow sheep utilizing mitochondrial cytochrome b gene.
A complete of 87 specimens from 5 totally different geographic places of Yakut snow sheep in addition to 20 specimens of different acknowledged subspecies have been included on this research. We recognized 19 haplotypes, two of which belonged to the inhabitants from Kharaulakh Ridge. Median-joining community and Bayesian tree analyses revealed that Kharaulakh inhabitants clustered individually from all the opposite Yakut snow sheep.
The divergence time between Kharaulakh inhabitants and Yakut snow sheep was estimated as 0.48 ± 0.19 MYA. Thus, the research of the mtDNA cytb sequences confirmed the outcomes of genome-wide SNP evaluation. Bearing in mind the excessive diploma of divergence of Kharaulakh snow sheep from different teams, recognized by each nuclear and mitochondrial DNA markers, we suggest to categorise the Kharaulakh inhabitants as a separate subspecies.
Mitochondrial DNA Profiles of People from a 12th Century Necropolis in Feldioara (Transylvania)
The genetic signature of contemporary Europeans is the cumulated results of millennia of discrete small-scale exchanges between a number of distinct inhabitants teams that carried out a repeated cycle of motion, settlement, and interactions with one another. On this research we aimed to focus on one such minute genetic cycle in a sea of genetic interactions by reconstructing a part of the genetic story of the migration, settlement, interplay, and legacy of what’s right this moment the Transylvanian Saxon
The evaluation of the mitochondrial DNA management area of 13 medieval people from Feldioara necropolis (Transylvania area, Romania) reveals a genetically heterogeneous group the place all recognized haplotypes are totally different. A lot of the perceived maternal lineages are of Western Eurasian origin, aside from the Central Asiatic haplogroup C seen in just one pattern. Comparisons with historic and trendy populations describe the contribution of the investigated Saxon settlers to the genetic historical past of this a part of Europe.
Full mitochondrial DNA sequence of Norwegian skates ( Raja brachyuran Lafont, 1871) imported to Korea
On this research, the entire mitochondrial genome of Norwegian skates imported to Korea was sequenced with a round molecule of 17,121 bp, which consisted of 13 protein-coding genes (PCGs), 2 ribosomal RNAs, 22 switch RNA genes, and a management area (D-loop). And amongst these sequences, 193 bp sequence within the D-loop of the genus Raja prompt the opportunity of getting used as a genetic marker for classification of Raja and Dipturus species.
) T4 DNA Ligase (Recombinant) |
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| abx073011-500000IU | Abbexa | 500.000 IU | EUR 1539 |
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) Thymine-DNA Glycosylase (Recombinant) |
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| 20-abx073364 | Abbexa |
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) Taq DNA Polymerase (Recombinant) |
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| abx073521-10000U | Abbexa | 10000 U | EUR 592 |
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Taq DNA Polymerase (Recombinant) |
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| abx073521-1000U | Abbexa | 1000 U | EUR 230 |
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Taq DNA Polymerase (Recombinant) |
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| abx073521-3000U | Abbexa | 3000 U | EUR 328 |
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) DNA Topoisomerase-I (Recombinant) |
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| 20-abx073616 | Abbexa |
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) Pfu DNA Polymerase (Recombinant) |
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| abx074017-100U | Abbexa | 100 U | EUR 328 |
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Pfu DNA Polymerase (Recombinant) |
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| abx074017-2500U | Abbexa | 2500 U | EUR 1274 |
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Pfu DNA Polymerase (Recombinant) |
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| abx074017-500U | Abbexa | 500 U | EUR 439 |
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 Recombinant Pfu DNA Polymerase |
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| 7-03322 | CHI Scientific | 100U | Ask for price |
Recombinant Pfu DNA Polymerase |
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| 7-03323 | CHI Scientific | 500U | Ask for price |
Recombinant Pfu DNA Polymerase |
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| 7-03324 | CHI Scientific | 2500U | Ask for price |
 Recombinant T4 DNA Ligase |
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| 7-03622 | CHI Scientific | 20,000IU | Ask for price |
Recombinant T4 DNA Ligase |
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| 7-03623 | CHI Scientific | 100,000IU | Ask for price |
Recombinant T4 DNA Ligase |
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| 7-03624 | CHI Scientific | 500,000IU | Ask for price |
 Recombinant Taq DNA Polymerase |
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| 7-03634 | CHI Scientific | 1,000U | Ask for price |
Recombinant Taq DNA Polymerase |
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| 7-03635 | CHI Scientific | 3,000U | Ask for price |
Recombinant Taq DNA Polymerase |
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| 7-03636 | CHI Scientific | 10,000U | Ask for price |
 Recombinant human DNA-directed DNA/RNA polymerase mu |
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| P2815 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA-directed DNA/RNA polymerase mu |
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 ELISA Kit) Mouse Anti-DNA Antibody (DNA) ELISA Kit |
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| abx257816-96tests | Abbexa | 96 tests | EUR 746 |
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 OGG1 8-Oxoguanine DNA Glycosylase Mouse Recombinant Protein |
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| PROTO08760 | BosterBio | Regular: 5ug | EUR 317 |
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Description: OGG1 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 368 amino acids (1-345 a.a) and having a molecular mass of 41.3kDa. OGG1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
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, beta (Recombinant)) Polymerase (DNA directed), beta (Recombinant) |
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| 20-abx073237 | Abbexa |
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) 8-Oxoguanine DNA Glycosylase (Recombinant) |
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| 20-abx073274 | Abbexa |
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) Taq Plus DNA Polymerase (Recombinant) |
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| abx073522-2500U | Abbexa | 2.500 U | EUR 592 |
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Taq Plus DNA Polymerase (Recombinant) |
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| abx073522-250U | Abbexa | 250 U | EUR 230 |
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Taq Plus DNA Polymerase (Recombinant) |
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| abx073522-750U | Abbexa | 750 U | EUR 328 |
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) N-Methylpurine-DNA Glycosylase (Recombinant) |
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| 20-abx073622 | Abbexa |
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, lambda (Recombinant)) Polymerase (DNA directed), lambda (Recombinant) |
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| 20-abx073724 | Abbexa |
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) E.Coli Formamidopyrimidine-DNA Glycosylase (Recombinant) |
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| 20-abx073795 | Abbexa |
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) Tyrosyl-DNA Phosphodiesterase 2 (Recombinant) |
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| 20-abx073819 | Abbexa |
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) E.Coli Adenine DNA Glycosylase (Recombinant) |
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| 20-abx074009 | Abbexa |
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 DNA-PKcs recombinant monoclonal antibody |
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| A5876 | Bimake | 100ul X 3 | EUR 595 |
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Description: A recombinant monoclonal antibody from rabbit against human DNA-PKcs for WB, IHC,ELISA |
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 Recombinant Taq Plus DNA Polymerase |
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| 7-03631 | CHI Scientific | 250U | Ask for price |
Recombinant Taq Plus DNA Polymerase |
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| 7-03632 | CHI Scientific | 750U | Ask for price |
Recombinant Taq Plus DNA Polymerase |
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| 7-03633 | CHI Scientific | 2,500U | Ask for price |
 Recombinant Human DNA Topoisomerase-I |
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| 7-03658 | CHI Scientific | 5µg | Ask for price |
Recombinant Human DNA Topoisomerase-I |
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| 7-03659 | CHI Scientific | 20µg | Ask for price |
Recombinant Human DNA Topoisomerase-I |
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| 7-03660 | CHI Scientific | 1mg | Ask for price |
) Recombinant DNA Methyltransferase 1 (DNMT1) |
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| 4-RPJ244Hu01 | Cloud-Clone |
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Description: Recombinant Human DNA Methyltransferase 1 expressed in: E.coli |
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) Recombinant DNA Methyltransferase 3B (DNMT3B) |
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| 4-RPJ246Mu01 | Cloud-Clone |
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Description: Recombinant Mouse DNA Methyltransferase 3B expressed in: E.coli |
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) Recombinant Uracil DNA Glycosylase (UNG) |
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| 4-RPG917Hu01 | Cloud-Clone |
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Description: Recombinant Human Uracil DNA Glycosylase expressed in: E.coli |
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 T4 DNA Ligase) Recombinant (E.Coli) T4 DNA Ligase |
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| RP-374 | Alpha Diagnostics | 20 KU | EUR 164 |
 Taq DNA Polymerase) Recombinant (E.Coli) Taq DNA Polymerase |
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| RP-394 | Alpha Diagnostics | 1000 IU | EUR 164 |
 Genomic DNA - Mouse Male |
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| D1334999-G01 | Biochain | 100 ug | EUR 188 |
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Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
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 Genomic DNA - Mouse Female |
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| D1334999-G02 | Biochain | 100 ug | EUR 188 |
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Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
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 Mouse Methylated DNA Control |
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| D6334149 | Biochain | 5 ug | Ask for price |
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Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
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) O-6-Methylguanine-DNA Methyltransferase (Recombinant) |
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| 20-abx073555 | Abbexa |
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) DNA Topoisomerase-I 70 kDa (Recombinant) |
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| 20-abx073615 | Abbexa |
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 DNA Ligase IV recombinant monoclonal antibody |
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| A5820 | Bimake | 100ul X 3 | EUR 595 |
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Description: A recombinant monoclonal antibody from rabbit against human DNA Ligase IV for WB, IHC, IF,ELISA |
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 DNA Polymerase beta recombinant monoclonal antibody |
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| A5473 | Bimake | 100ul X 3 | EUR 595 |
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Description: A recombinant monoclonal antibody from rabbit against human DNA Polymerase beta for WB,ELISA |
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 Recombinant Human N-Methylpurine-DNA Glycosylase |
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| 7-03169 | CHI Scientific | 2µg | Ask for price |
Recombinant Human N-Methylpurine-DNA Glycosylase |
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| 7-03170 | CHI Scientific | 10µg | Ask for price |
Recombinant Human N-Methylpurine-DNA Glycosylase |
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| 7-03171 | CHI Scientific | 1mg | Ask for price |
 Recombinant Human 8-Oxoguanine DNA Glycosylase |
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| 7-03277 | CHI Scientific | 5µg | Ask for price |
Recombinant Human 8-Oxoguanine DNA Glycosylase |
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| 7-03278 | CHI Scientific | 20µg | Ask for price |
Recombinant Human 8-Oxoguanine DNA Glycosylase |
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| 7-03279 | CHI Scientific | 1mg | Ask for price |
 Recombinant Human DNA Topoisomerase-I 70kDa |
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| 7-03661 | CHI Scientific | 5µg | Ask for price |
Recombinant Human DNA Topoisomerase-I 70kDa |
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| 7-03662 | CHI Scientific | 20µg | Ask for price |
Recombinant Human DNA Topoisomerase-I 70kDa |
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| 7-03663 | CHI Scientific | 1mg | Ask for price |
 TOP1 DNA Topoisomerase-IHuman Recombinant Protein |
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| PROTP11387-1 | BosterBio | Regular: 20ug | EUR 317 |
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Description: DNA Topoisomerase-I Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 91,576 Dalton (excluding glycosilation) 102 kDa total mass. The TOP1 is expressed with a -6xHis tag and purified by proprietary chromatographic techniques. |
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 Recombinant human DNA repair protein REV1 |
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| P2230 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA repair protein REV1 |
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 Recombinant human DNA topoisomerase I, mitochondrial |
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| P2243 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA topoisomerase I, mitochondrial |
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 Recombinant human DNA-binding protein RFXANK |
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| P2771 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA-binding protein RFXANK |
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 Recombinant human DNA-binding protein RFX2 |
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| P2855 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA-binding protein RFX2 |
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) Recombinant N-Methylpurine DNA Glycosylase (MPG) |
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| 4-RPH625Hu01 | Cloud-Clone |
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Description: Recombinant Human N-Methylpurine DNA Glycosylase expressed in: E.coli |
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Recombinant N-Methylpurine DNA Glycosylase (MPG) |
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| 4-RPH625Mu01 | Cloud-Clone |
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Description: Recombinant Mouse N-Methylpurine DNA Glycosylase expressed in: E.coli |
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Recombinant N-Methylpurine DNA Glycosylase (MPG) |
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| 4-RPH625Ra01 | Cloud-Clone |
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Description: Recombinant Rat N-Methylpurine DNA Glycosylase expressed in: E.coli |
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) Recombinant DNA Repair Protein RAD50 (RAD50) |
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| 4-RPK111Hu01 | Cloud-Clone |
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Description: Recombinant Human DNA Repair Protein RAD50 expressed in: E.coli |
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Recombinant DNA Repair Protein RAD50 (RAD50) |
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| 4-RPK111Hu02 | Cloud-Clone |
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Description: Recombinant Human DNA Repair Protein RAD50 expressed in: E.coli |
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Recombinant DNA Repair Protein RAD50 (RAD50) |
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| 4-RPK111Mu01 | Cloud-Clone |
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Description: Recombinant Mouse DNA Repair Protein RAD50 expressed in: E.coli |
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) Recombinant Tyrosyl DNA Phosphodiesterase 1 (TDP1) |
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| 4-RPC785Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Tyrosyl DNA Phosphodiesterase 1 expressed in: E.coli |
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Recombinant Tyrosyl DNA Phosphodiesterase 1 (TDP1) |
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| 4-RPC785Ra01 | Cloud-Clone |
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Description: Recombinant Rat Tyrosyl DNA Phosphodiesterase 1 expressed in: E.coli |
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 Taq Plus DNA Polymerase) Recombinant (E.Coli) Taq Plus DNA Polymerase |
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| RP-395 | Alpha Diagnostics | 250 U | EUR 164 |
 Mouse DNA- directed DNA/RNA polymerase mu, Polm ELISA KIT |
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| ELI-32836m | Lifescience Market | 96 Tests | EUR 865 |
 Mouse Anti-DNA ELISA Kit |
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| EMD0216 | Abclonal | 96Tests | EUR 521 |
 DiscoveryProbe? DNA Damage/DNA Repair Library |
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| L1033-.1 | ApexBio | 100 uL/well(10 mM solution) | EUR 3889 |
DiscoveryProbe? DNA Damage/DNA Repair Library |
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| L1033-.25 | ApexBio | 250 uL/well(10 mM solution) | EUR 6905 |
DiscoveryProbe? DNA Damage/DNA Repair Library |
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| L1033-5 | ApexBio | 5 mg/well | EUR 9005 |
) Recombinant Human DNA Polymerase β (C-6His) |
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| C159-10ug | Novoprotein | 10ug | EUR 156 |
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Description: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8. |
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Recombinant Human DNA Polymerase β (C-6His) |
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| C159-1mg | Novoprotein | 1mg | EUR 2283 |
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Description: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8. |
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Recombinant Human DNA Polymerase β (C-6His) |
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| C159-500ug | Novoprotein | 500ug | EUR 1613 |
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Description: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8. |
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Recombinant Human DNA Polymerase β (C-6His) |
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| C159-50ug | Novoprotein | 50ug | EUR 369 |
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Description: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8. |
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) DNA Cytosine-5--Methyltransferase 3-Like (Recombinant) |
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| 20-abx073992 | Abbexa |
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 Recombinant Human O-6-Methylguanine-DNA Methyltransferase |
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| 7-03133 | CHI Scientific | 5µg | Ask for price |
Recombinant Human O-6-Methylguanine-DNA Methyltransferase |
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| 7-03134 | CHI Scientific | 20µg | Ask for price |
Recombinant Human O-6-Methylguanine-DNA Methyltransferase |
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| 7-03135 | CHI Scientific | 1mg | Ask for price |
 Recombinant Human DNA Damage Inducible Transcript 3 |
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| 7-04969 | CHI Scientific | 5µg | Ask for price |
Recombinant Human DNA Damage Inducible Transcript 3 |
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| 7-04970 | CHI Scientific | 20µg | Ask for price |
Recombinant Human DNA Damage Inducible Transcript 3 |
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| 7-04971 | CHI Scientific | 1mg | Ask for price |
 Recombinant Human DNA Damage Inducible Transcript 4 |
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| 7-04972 | CHI Scientific | 2µg | Ask for price |
Recombinant Human DNA Damage Inducible Transcript 4 |
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| 7-04973 | CHI Scientific | 10µg | Ask for price |
Recombinant Human DNA Damage Inducible Transcript 4 |
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| 7-04974 | CHI Scientific | 1mg | Ask for price |
 Recombinant Human DNA Fragmentation Factor Subunit Alpha |
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| 7-04978 | CHI Scientific | 5µg | Ask for price |
Recombinant Human DNA Fragmentation Factor Subunit Alpha |
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| 7-04979 | CHI Scientific | 25µg | Ask for price |
Recombinant Human DNA Fragmentation Factor Subunit Alpha |
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| 7-04980 | CHI Scientific | 1mg | Ask for price |
 MUTM Formamidopyrimidine-DNA Glycosylase E.Coli Recombinant Protein |
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| PROTP05523 | BosterBio | Regular: 10ug | EUR 317 |
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Description: MUTM Recombinant produced in E. coli is a single polypeptide chain containing 289 amino acids (1-269) and having a molecular mass of 32.4kDa.;MUTM is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
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 UNG Uracil DNA Glycosylase E.Coli Recombinant Protein |
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| PROTP12295 | BosterBio | Regular: 10ug | EUR 317 |
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Description: UNG E.Coli Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 252 amino acids (1-229 a.a) and having a molecular mass of 28.1kDa. |
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 MutY Adenine DNA Glycosylase E.Coli Recombinant Protein |
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| PROTP17802 | BosterBio | Regular: 5ug | EUR 317 |
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Description: MutY Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 373 amino acids (1-350) and having a molecular mass of 41.5kDa. MutY is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
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 Recombinant human DNA-directed RNA polymerase, mitochondrial |
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| P2352 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA-directed RNA polymerase, mitochondrial |
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 Recombinant human DNA polymerase delta subunit 2 |
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| P2733 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA polymerase delta subunit 2 |
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 Recombinant human DNA polymerase subunit gamma-1 |
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| P2838 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA polymerase subunit gamma-1 |
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) Recombinant DNA Damage Inducible Transcript 3 (DDIT3) |
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| 4-RPJ282Hu01 | Cloud-Clone |
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Description: Recombinant Human DNA Damage Inducible Transcript 3 expressed in: E.coli |
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Recombinant DNA Damage Inducible Transcript 3 (DDIT3) |
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| 4-RPJ282Mu01 | Cloud-Clone |
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Description: Recombinant Mouse DNA Damage Inducible Transcript 3 expressed in: E.coli |
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) Recombinant DNA Fragmentation Factor Subunit Alpha (DFFa) |
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| 4-RPL426Hu01 | Cloud-Clone |
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Description: Recombinant Human DNA Fragmentation Factor Subunit Alpha expressed in: E.coli |
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Recombinant DNA Fragmentation Factor Subunit Alpha (DFFa) |
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| 4-RPL426Mu01 | Cloud-Clone |
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Description: Recombinant Mouse DNA Fragmentation Factor Subunit Alpha expressed in: E.coli |
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) Recombinant Polymerase DNA Directed Gamma 1 (POLg1) |
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| 4-RPF723Hu01 | Cloud-Clone |
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Description: Recombinant Human Polymerase DNA Directed Gamma 1 expressed in: E.coli |
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) Recombinant Z-DNA Binding Protein 1 (ZBP1) |
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| 4-RPB552Hu01 | Cloud-Clone |
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Description: Recombinant Human Z-DNA Binding Protein 1 expressed in: E.coli |
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) Recombinant Polymerase DNA Directed Alpha 1 (POLa1) |
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| 4-RPC713Hu01 | Cloud-Clone |
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Description: Recombinant Human Polymerase DNA Directed Alpha 1 expressed in: E.coli |
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Recombinant Polymerase DNA Directed Alpha 1 (POLa1) |
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| 4-RPC713Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Polymerase DNA Directed Alpha 1 expressed in: E.coli |
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) Recombinant Polymerase DNA Directed Delta 1 (POLd) |
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| 4-RPC717Hu01 | Cloud-Clone |
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Description: Recombinant Human Polymerase DNA Directed Delta 1 expressed in: E.coli |
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) Recombinant Tar DNA Binding Protein 43kDa (TDP43) |
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| 4-RPB951Hu01 | Cloud-Clone |
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Description: Recombinant Human Tar DNA Binding Protein 43kDa expressed in: E.coli |
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Recombinant Tar DNA Binding Protein 43kDa (TDP43) |
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| 4-RPB951Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Tar DNA Binding Protein 43kDa expressed in: E.coli |
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) Recombinant O-6-Methylguanine DNA Methyltransferase (MGMT) |
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| 4-RPC027Hu01 | Cloud-Clone |
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Description: Recombinant Human O-6-Methylguanine DNA Methyltransferase expressed in: E.coli |
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Recombinant O-6-Methylguanine DNA Methyltransferase (MGMT) |
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| 4-RPC027Ra01 | Cloud-Clone |
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Description: Recombinant Rat O-6-Methylguanine DNA Methyltransferase expressed in: E.coli |
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) Recombinant ATP Dependent DNA ligase I (LIG1) |
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| 4-RPB269Hu01 | Cloud-Clone |
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Description: Recombinant Human ATP Dependent DNA ligase I expressed in: E.coli |
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Recombinant ATP Dependent DNA ligase I (LIG1) |
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| 4-RPB269Ra01 | Cloud-Clone |
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Description: Recombinant Rat ATP Dependent DNA ligase I expressed in: E.coli |
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 TDG Thymine-DNA Glycosylase Human Recombinant Protein |
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| PROTQ13569 | BosterBio | Regular: 20ug | EUR 317 |
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Description: TDG Human Recombinant produced in E. coli is a single polypeptide chain containing 433 amino acids (1-410) and having a molecular mass of 48.4 kDa.;TDG is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
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 Recombinant CMV ICP36 DNA Binding Protein [GST] |
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| VAng-Lsx0042-inquire | Creative Biolabs | inquire | Ask for price |
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Description: CMV ICP36 DNA Binding Protein [GST], recombinant protein from E. coli. |
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 pUC18 DNA |
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| G40-300 | GeneOn | 50µg | EUR 56 |
pUC18 DNA |
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| G40-305 | GeneOn | 5x50µg | EUR 147 |
 DNA Antibody |
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| abx023805-02mg | Abbexa | 0.2 mg | EUR 648 |
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 DNA Polymerase |
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| ABF5235 | Lifescience Market | 100 ug | EUR 438 |
 DNA pol |
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| ABF9055 | Lifescience Market | 100 ug | EUR 438 |
DNA Polymerase |
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| ABD3082 | Lifescience Market | 100 ug | EUR 438 |
 DNA antibody |
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| 10C-CR6034M1 | Fitzgerald | 100 ug | EUR 241 |
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Description: Mouse monoclonal DNA antibody |
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DNA antibody |
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| 10-D20A | Fitzgerald | 500 ug | EUR 493 |
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Description: Mouse monoclonal DNA antibody |
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DNA antibody |
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| 10R-D114b | Fitzgerald | 100 ug | EUR 560 |
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Description: Mouse monoclonal DNA antibody |
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 T7 DNA |
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| 310-005 | GeneOn | 200µg | EUR 82 |
T7 DNA |
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| 310-025 | GeneOn | 5x200 µg | EUR 225 |
 DNA-Fect |
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| DF37100-1 | Neuromics | 1 ml | EUR 349 |
 DNA-Fect293 |
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| DF37293-1 | Neuromics | 1 ml | EUR 291 |
 pBR322 DNA |
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| MSD14 | Bio Basic | 50ug | EUR 152.66 |
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 DNA-fectamine |
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| DNAF001 | Bio Basic | 1ml | EUR 278.81 |
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 Protein) Mouse DNA Methyltransferase 3B (DNMT3B) Protein |
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| 20-abx650756 | Abbexa |
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 Protein) Mouse DNA Methyltransferase 1 (DNMT1) Protein |
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| 20-abx653198 | Abbexa |
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Mouse DNA Methyltransferase 1 (DNMT1) Protein |
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| 20-abx653199 | Abbexa |
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 Mouse Uracil DNA Glycosylase ELISA kit |
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| E03U0076-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Uracil DNA Glycosylase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Uracil DNA Glycosylase ELISA kit |
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| E03U0076-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Uracil DNA Glycosylase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Uracil DNA Glycosylase ELISA kit |
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| E03U0076-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Uracil DNA Glycosylase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Mouse DNA Methyltransferase 1 ELISA kit |
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| E03D0320-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA Methyltransferase 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse DNA Methyltransferase 1 ELISA kit |
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| E03D0320-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA Methyltransferase 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse DNA Methyltransferase 1 ELISA kit |
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| E03D0320-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA Methyltransferase 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Mouse DNA Methyltransferase 3A ELISA kit |
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| E03D0321-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA Methyltransferase 3A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse DNA Methyltransferase 3A ELISA kit |
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| E03D0321-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA Methyltransferase 3A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse DNA Methyltransferase 3A ELISA kit |
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| E03D0321-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA Methyltransferase 3A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Mouse DNA Methyltransferase 3beta ELISA kit |
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| E03D0322-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA Methyltransferase 3beta in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse DNA Methyltransferase 3beta ELISA kit |
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| E03D0322-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA Methyltransferase 3beta in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse DNA Methyltransferase 3beta ELISA kit |
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| E03D0322-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA Methyltransferase 3beta in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 ELISA kit) Mouse DNA (Double Stranded) ELISA kit |
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| E03A0440-192T | B-Gene | 192 tests | EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA (Double Stranded) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse DNA (Double Stranded) ELISA kit |
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| E03A0440-48 | B-Gene | 1 plate of 48 wells | EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA (Double Stranded) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse DNA (Double Stranded) ELISA kit |
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| E03A0440-96 | B-Gene | 1 plate of 96 wells | EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Mouse DNA (Double Stranded) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 ELISA Kit) Anti-DNA antibody (Mouse) ELISA Kit |
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| E4355-100 | Biovision | EUR 892 | |
 Mouse DNA nucleotidylexotransferase, Dntt ELISA KIT |
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| ELI-05097m | Lifescience Market | 96 Tests | EUR 865 |
 Anti-DNA antibody ELISA Kit| Mouse |
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| EF013986 | Lifescience Market | 96 Tests | EUR 689 |
 Mouse N-DNA-AB ELISA Kit |
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| EMN0082 | Abclonal | 96Tests | EUR 521 |
 Mouse Anti Human Dna Monoclonal Antibody |
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| DMABT-52214MH | Creative Diagnostics | 0.1 mg | EUR 767 |
 Mouse Mitochondrial DNA Copy Number Kit |
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| MCN3 | Detroit R&D | 1 Kit | EUR 349 |
 Mouse DNA Damage Signaling Primer Library |
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| MDDS-I | Real Time Primers | 1 set | EUR 548 |
 Mouse DNA Repair Primer Library I |
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| MDRL-I | Real Time Primers | 1 set | EUR 645 |
 Mouse DNA Repair Primer Library II |
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| MDRL-II | Real Time Primers | 1 set | EUR 645 |
ELISA Kit) Mouse DNA methyltransferase(DNAM)ELISA Kit |
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| QY-E20479 | Qayee Biotechnology | 96T | EUR 361 |
ELISA Kit) Mouse DNA methyltransferase3α(DNAM3α)ELISA Kit |
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| QY-E20480 | Qayee Biotechnology | 96T | EUR 361 |
 Mouse Real-time PCR DNA Quantitation after QPCR DNA Damage Analysis Kit |
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| DD2M | Detroit R&D | 1 Kit | EUR 430 |
 , DNA Aptamer, Biotinylated) Taq DNA polymerase (TQ21) , DNA Aptamer, Biotinylated |
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| AD-146-B | Alpha Diagnostics | Custom | Ask for price |
 , DNA Aptamer, unlabeled) Taq DNA polymerase (TQ21) , DNA Aptamer, unlabeled |
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| AD-146-U | Alpha Diagnostics | Custom | Ask for price |
 Antibody) DNA Ligase I (DNA Ligase I) Antibody |
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| abx232431-100ug | Abbexa | 100 ug | EUR 481 |
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 DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free) |
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| N150 | GeneOn | 500 units | EUR 102 |
DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free) |
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| N152 | GeneOn | 5x500 units | EUR 394 |
DFS-"HOT" Taq DNA Polymerase (DNA-free sensitive, E-coli. DNA Free) |
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| N154 | GeneOn | 20x500 units | EUR 1525 |
) E.Coli G / U Mismatch-Specific DNA Glycosylase (Recombinant) |
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| 20-abx073820 | Abbexa |
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, human recombinant) DNA Binding Protein-7 (DBP-7), human recombinant |
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| 7603-100 | Biovision | EUR 588 | |
DNA Binding Protein-7 (DBP-7), human recombinant |
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| 7603-1000 | Biovision | EUR 3258 | |
DNA Binding Protein-7 (DBP-7), human recombinant |
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| 7603-20 | Biovision | EUR 245 | |
 Recombinant Human Chromodomain Helicase DNA Binding Protein 4 |
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| 7-04792 | CHI Scientific | 5µg | Ask for price |
Recombinant Human Chromodomain Helicase DNA Binding Protein 4 |
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| 7-04793 | CHI Scientific | 20µg | Ask for price |
Recombinant Human Chromodomain Helicase DNA Binding Protein 4 |
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| 7-04794 | CHI Scientific | 1mg | Ask for price |
 Recombinant Human p53 and DNA-Damage Regulated 1 |
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| 7-05842 | CHI Scientific | 5µg | Ask for price |
Recombinant Human p53 and DNA-Damage Regulated 1 |
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| 7-05843 | CHI Scientific | 20µg | Ask for price |
Recombinant Human p53 and DNA-Damage Regulated 1 |
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| 7-05844 | CHI Scientific | 1mg | Ask for price |
 Recombinant human Chromodomain-helicase-DNA-binding protein 8 |
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| P1743 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human Chromodomain-helicase-DNA-binding protein 8 |
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 Recombinant human DNA-binding protein inhibitor ID-1 |
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| P1872 | FN Test | 100ug | Ask for price |
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Description: Recombinant protein for human DNA-binding protein inhibitor ID-1 |
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 OGG1 8-Oxoguanine DNA Glycosylase Human Recombinant Protein |
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| PROTO15527 | BosterBio | Regular: 25ug | EUR 317 |
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Description: OGG1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 368 amino acids (1-345 a.a.) and having a molecular mass of 41.2 kDa. The OGG1 is fused to 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
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 TDP2 Tyrosyl-DNA Phosphodiesterase 2 Human Recombinant Protein |
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| PROTO95551 | BosterBio | Regular: 10ug | EUR 317 |
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Description: TDP2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 385 amino acids (1-362) and having a molecular mass of 43.3kDa. ;TDP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
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, Beta Human Recombinant Protein) POLB Polymerase (DNA directed), Beta Human Recombinant Protein |
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| PROTP06746 | BosterBio | Regular: 20ug | EUR 317 |
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Description: POLB Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 355 amino acids (1-335 a.a) and having a molecular mass of 40.3kDa.;POLB is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
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 TOP1 DNA Topoisomerase-I 70kDa Recombinant Protein Human |
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| PROTP11387 | BosterBio | Regular: 20ug | EUR 317 |
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Description: Recombinant TOP1 70kDa protein is an enzyme fragment having a molecular mass of 69,199 Dalton (pH 9.4). TOP1 70kDa protein is fused to a hexa-histidine purification tag. |
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 TDP1 Tyrosyl-DNA Phosphodiesterase 1 Human Recombinant Protein |
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| PROTQ9NUW8 | BosterBio | Regular: 20ug | EUR 317 |
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Description: TDP1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 318 amino acids (1-298) and having a molecular mass of 35.8kDa. TDP1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
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The BI phylogenetic tree through the use of the nucleotide sequences of 13 PCGs from 15 obtainable mitogenomes of household Rajidae confirmed additionally that Norwegian skates imported to Korea type a gaggle with Raja brachyura species with excessive department worth, and that this was a species of Raja brachyura. As above, these outcomes can be anticipated to supply for the additional understanding on the phylogenetic relationship, taxonomic classification and phylogeography of the household Rajidae.
