• April 23, 2021
Mitochondrial genome stability in human: understanding the role of DNA repair pathways

Mitochondrial genome stability in human: understanding the role of DNA repair pathways

Mitochondria are semiautonomous organelles in eukaryotic cells and possess their very own genome that replicates independently. Mitochondria play a significant function in oxidative phosphorylation on account of which its genome is often uncovered to oxidative stress. Components together with ionizing radiation, radiomimetic medication and replication fork stalling also can lead to several types of mutations in mitochondrial DNA (mtDNA) resulting in genome fragility.
Mitochondria from myopathies, dystonia, most cancers affected person samples present frequent mtDNA mutations reminiscent of level mutations, insertions and large-scale deletions that would account for mitochondria-associated illness pathogenesis. The mechanism by which such mutations come up following publicity to numerous DNA-damaging brokers isn’t nicely understood. One of many well-studied restore pathways in mitochondria is base excision restore.
Different restore pathways reminiscent of mismatch restore, homologous recombination and microhomology-mediated finish becoming a member of have additionally been reported. Curiously, nucleotide excision restore and classical nonhomologous DNA finish becoming a member of should not detected in mitochondria. On this assessment, we summarize the potential causes of mitochondrial genome fragility, their implications in addition to numerous DNA restore pathways that function in mitochondria.

Lack of Mitochondrial Protease CLPP Prompts Sort I IFN Responses via the Mitochondrial DNA-cGAS-STING Signaling Axis

Caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) is a serine protease that degrades broken or misfolded mitochondrial proteins. CLPP-null mice exhibit progress retardation, deafness, and sterility, resembling human Perrault syndrome, but additionally show immune system alterations. Nevertheless, the molecular mechanisms and signaling pathways underlying immunological modifications in CLPP-null mice stay unclear.
On this research, we report the steady-state activation of sort I IFN signaling and antiviral gene expression in CLPP-deficient cells and tissues, leading to marked resistance to RNA and DNA virus an infection. Depletion of the cyclic GMP-AMP (cGAS)-stimulator of IFN genes (STING) DNA sensing pathway reduces steady-state IFN-I signaling and abrogates the broad antiviral phenotype of CLPP-null cells. Furthermore, we report that CLPP deficiency results in mitochondrial DNA (mtDNA) instability and packaging alterations.
Pharmacological and genetic approaches to deplete mtDNA or inhibit cytosolic launch markedly scale back antiviral gene expression, implicating mtDNA stress as the driving force of IFN-I signaling in CLPP-null mice. Our work locations the cGAS-STING-IFN-I innate immune pathway downstream of CLPP and should have implications for understanding Perrault syndrome and different human ailments involving CLPP dysregulation.

Mitochondrial DNA from osteoarthritic sufferers drives purposeful impairment of mitochondrial exercise: a research on transmitochondrial cybrids

With the redefinition of osteoarthritis (OA) and the understanding that the joint behaves as an organ, OA is now thought of a systemic sickness with a low grade of power irritation. Mitochondrial dysfunction is nicely documented in OA and has the capability to change chondrocyte and synoviocyte perform. Transmitochondrial cybrids are steered as a helpful mobile mannequin to review mitochondrial biology in vitro, as they carry totally different mitochondrial variants with the identical nuclear background.
The purpose of this work was to review mitochondrial and metabolic perform of cybrids with mitochondrial DNA from wholesome (N) and OA donors. On this work, the authors exhibit that cybrids from OA sufferers behave otherwise from cybrids from N donors in a number of mitochondrial parameters. Moreover, OA cybrids behave equally to OA chondrocytes. These outcomes improve our understanding of the function of mitochondria within the degeneration strategy of OA and current cybrids as a helpful mannequin to review OA pathogenesis.

Mitochondrial DNA permits AIM2 inflammasome activation and hepatocyte pyroptosis in non-alcoholic fatty liver illness

Nonalcoholic fatty liver illness (NAFLD) is typified by accumulating extra liver triacylglycerol, irritation, and liver dysfunction. This research was aimed to analyze the function of mitochondrial DNA synthesis-induced activation of Absent in melanoma 2 (AIM2) inflammasome and pyroptosis in NAFLD. Mice had been raised on a high-fat food plan for 24 weeks to ascertain NAFLD fashions. F4/80 immunofluorescence was carried out to mirror the inflammatory response within the liver of mice. Western blot, ELISA, and immunofluorescence had been adopted to find out the expression of AIM2 inflammasome-related proteins and components.
EdU immunofluorescence was utilized for the examination of mitochondrial DNA expression and circulation cytometry for cell pyroptosis. Agarose gel electrophoresis was used to detect the integrity of extracted mouse mitochondrial DNA (mtDNA). The degrees of AIM2 inflammasome-related proteins within the liver and the degrees of IL-1β and IL-18 in serum had been elevated in high-fat diet-induced NAFLD mice. AIM2 inflammasome activation and pyroptosis had been triggered, and suppressed activation of AIM2 inflammasome alleviated the irritation and pyroptosis within the liver of NAFLD mice. Mitochondria had been severely broken and mtDNA was synthesized after NAFLD modeling.
Mitochondrial genome stability in human: understanding the role of DNA repair pathways
Additional, mtDNA therapy may promote palmitate (PA)-induced activation of AIM2 inflammasome and pyroptosis. Furthermore, inhibition of IRF1 gene alleviated PA-induced AIM2 inflammasome activation and pyroptosis. In conclusion, mitochondrial DNA synthesis may allow AIM2 inflammasome activation and induce the hepatocyte pyroptosis, thereby exacerbating NAFLD.

Haplotypes traceability and genetic variability of the breeding inhabitants of pacu (Piaractus mesopotamicus) revealed by mitochondrial DNA

The principle goal of this research was to estimate the genetic range ranges and haplotype traceability in pacu Piaractus mesopotamicus from the breeding program positioned in Brazil by analyses of the mitochondrial DNA management area (mtDNA). Furthermore, broodstocks from eight business fish farms had been used for comparative analysis, 4 from Brazil (Br1-Br4) and 4 from Argentina (Ar1-Ar4). The descriptive outcomes revealed 47 polymorphic websites and 51 mutations, which evidenced 34 haplotypes. Ten haplotypes had been shared amongst fish farms and 24 had been unique.
The nucleotide range (π) ranged from 0.00031 to 0.01462 and haplotype range (Hd) from 0.125 to 0.868. The evaluation of molecular variance (AMOVA) indicated excessive construction current within the analyzed shares (FST = 0.13356 and ФST = 0.52707). The genetic range was excessive in a lot of the business broodstocks, particularly these from Brazil. We noticed seven haplotypes within the genetic breeding inhabitants, of which 4 had been unique and three shared among the many business fish farms.

E. coli DNA Gyrase

TG2000G-7 2000 units
EUR 1836

S. aureus DNA Gyrase

TG2000GSA-1 100 units
EUR 403

S. aureus DNA Gyrase

TG2000GSA-3 500 units
EUR 716

S. aureus DNA Gyrase

TG2000GSA-5 1000 units
EUR 1052

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (50ug Relaxed DNA + 100u Gyrase)

TG2000G-1KIT 100 assays
EUR 380

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (250ug Relaxed DNA + 500u Gyrase)

TG2000G-3KIT 500 assays
EUR 985

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (500ug Relaxed DNA + 1000u Gyrase)

TG2000G-5KIT 1000 assays
EUR 1612

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (1mg Relaxed DNA + 2000u Gyrase)

TG2000G-7KIT 2000 assays
EUR 2844

Purified E. coli DNA Gyrase Drug Screening Kit (50ug Relaxed DNA + 100u Gyrase)

TG2001G-1KIT 100 assays
EUR 414

Purified E. coli DNA Gyrase Drug Screening Kit (250ug Relaxed DNA + 500u Gyrase)

TG2001G-3KIT 500 assays
EUR 1052

Purified E. coli DNA Gyrase Drug Screening Kit (500ug Relaxed DNA + 1000u Gyrase)

TG2001G-5KIT 1000 assays
EUR 1836

Purified E. coli DNA Gyrase Drug Screening Kit (1mg Relaxed DNA + 2000u Gyrase)

TG2001G-7KIT 2000 assays
EUR 2956

Acinetobacter

PVT14723 2 ug
EUR 703

100 BP DNA LADDER, 500UL PER KIT

M-DNA-100BP 1/pk
EUR 73
Description: Bioscience Mol Bio; DNA Ladder

1 KB DNA LADDER, 500UL PER KIT

M-DNA-1KB 1/pk
EUR 70
Description: Bioscience Mol Bio; DNA Ladder

metallo-b-lactamase inhibitor, DNA aptamer, Biotinylated

AD-159-B Custom Ask for price

Multivalent B-cell receptor specific, DNA apatamer, Biotinylated

AD-156-B Custom Ask for price

Acinetobacter baumannii PCR kit

PCR-H681-48D 50T
EUR 425.8
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Acinetobacter baumannii

Acinetobacter baumannii PCR kit

PCR-H681-96D 100T
EUR 521.5
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Acinetobacter baumannii

Gyrase Assay Buffer 5x

TG4030 1ml
EUR 145

Platelet-Derived Growth Factor B-chain (36t), DNA Aptamer, Biotinylated

AD-136-B Custom Ask for price

ELISA kit for Rat DNA polymerase alpha subunit B

EK3396 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat DNA polymerase alpha subunit B in samples from serum, plasma, tissue homogenates and other biological fluids.

Rat Pola2/ DNA polymerase alpha subunit B ELISA Kit

E0777Ra 1 Kit
EUR 646

Human POLA2/ DNA polymerase alpha subunit B ELISA Kit

E1985Hu 1 Kit
EUR 605

Bovine DNA polymerase alpha subunit B, POLA2 ELISA KIT

ELI-09178b 96 Tests
EUR 928

Human DNA polymerase alpha subunit B, POLA2 ELISA KIT

ELI-26200h 96 Tests
EUR 824

Mouse DNA polymerase alpha subunit B, Pola2 ELISA KIT

ELI-26201m 96 Tests
EUR 865

Rat Pola2(DNA polymerase alpha subunit B) ELISA Kit

ER0533 96T
EUR 567.6
  • Detection range: 31.25-2000 pg/ml
  • Uniprot ID: O89043
  • Alias: Pola2/DNA polymerase alpha subunit B/DNA polymerase alpha 70 kDa subunit/DNA polymerase subunit II
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 18.75pg/ml

Acinetobacter baumannii RT PCR kit

RTq-H681-100D 100T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Acinetobacter baumannii .

Acinetobacter baumannii RT PCR kit

RTq-H681-150D 150T
EUR 701
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Acinetobacter baumannii .

Acinetobacter baumannii RT PCR kit

RTq-H681-50D 50T
EUR 532.8
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Acinetobacter baumannii .

5X SA Gyrase Assay Buffer

TG4045 1ml
EUR 156

Recombinant Human DNA Fragmentation Factor Subunit Alpha

7-04978 5µg Ask for price

Recombinant Human DNA Fragmentation Factor Subunit Alpha

7-04979 25µg Ask for price

Recombinant Human DNA Fragmentation Factor Subunit Alpha

7-04980 1mg Ask for price

Recombinant human DNA polymerase delta subunit 2

P2733 100ug Ask for price
  • Uniprot ID: P49005
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for human DNA polymerase delta subunit 2

Recombinant human DNA polymerase subunit gamma-1

P2838 100ug Ask for price
  • Uniprot ID: P54098
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for human DNA polymerase subunit gamma-1

Recombinant DNA Fragmentation Factor Subunit Alpha (DFFa)

4-RPL426Hu01
  • EUR 499.62
  • EUR 236.00
  • EUR 1598.56
  • EUR 599.52
  • EUR 1099.04
  • EUR 397.00
  • EUR 3846.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: O00273
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 32.1kDa
  • Isoelectric Point: 4.8
Description: Recombinant Human DNA Fragmentation Factor Subunit Alpha expressed in: E.coli

Recombinant DNA Fragmentation Factor Subunit Alpha (DFFa)

4-RPL426Mu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: O70302
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 30.7kDa
  • Isoelectric Point: Inquire
Description: Recombinant Mouse DNA Fragmentation Factor Subunit Alpha expressed in: E.coli

Taq DNA polymerase (TQ21) , DNA Aptamer, Biotinylated

AD-146-B Custom Ask for price

Fmoc-b,b-diphenyl-Ala-OH

B-2725.0250 250.0mg
EUR 139
Description: Sum Formula: C30H25NO4; CAS# [201484-50-6]

Fmoc-b,b-diphenyl-Ala-OH

B-2725.1000 1.0g
EUR 357
Description: Sum Formula: C30H25NO4; CAS# [201484-50-6]

Fmoc-b,b-diphenyl-Ala-OH

B-2725.5000 5.0g
EUR 1336
Description: Sum Formula: C30H25NO4; CAS# [201484-50-6]

Acinetobacter baumannii Elongation factor Tu (tuf1)

1-CSB-EP025342AUD
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 58.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Acinetobacter baumannii Elongation factor Tu(tuf1) expressed in E.coli

Acinetobacter calcoaceticus Catechol 1, 2-dioxygenase

1-CSB-EP306913AWR
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 21.7 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Acinetobacter calcoaceticus Catechol 1,2-dioxygenase expressed in E.coli

Acinetobacter baumannii Beta-lactamase (NDM-1)

1-CSB-RP076174Ba
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 22 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Acinetobacter baumannii Beta-lactamase(NDM-1),partial expressed in E.coli

Acinetobacter baumannii Elongation factor Tu (tuf1)

1-CSB-YP025342AUD
  • EUR 679.00
  • EUR 335.00
  • EUR 2172.00
  • EUR 1051.00
  • EUR 1442.00
  • EUR 435.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 44.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Acinetobacter baumannii Elongation factor Tu(tuf1) expressed in Yeast

Acinetobacter baumannii One-Step PCR kit

Oneq-H681-100D 100T
EUR 747.4
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Acinetobacter baumannii.

Acinetobacter baumannii One-Step PCR kit

Oneq-H681-150D 150T
EUR 838.75
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Acinetobacter baumannii.

Acinetobacter baumannii One-Step PCR kit

Oneq-H681-50D 50T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Acinetobacter baumannii.

Human Neutrophil Elastase (DNA I) , DNA Aptamer, Biotinylated

AD-155-B Custom Ask for price

Pola2 ELISA Kit| Rat DNA polymerase alpha subunit B ELISA Kit

EF017366 96 Tests
EUR 689

Adenosine, DNA Aptamer, Biotinylated

AD-103-B Custom Ask for price

DNA Helicase B (HELB) Antibody

abx233821-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

DNA pol ? B Polyclonal Antibody

ABP52796-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human DNA pol ? B
  • Applications tips:
Description: A polyclonal antibody for detection of DNA pol ? B from Human. This DNA pol ? B antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNA pol ? B

DNA pol ? B Polyclonal Antibody

ABP52796-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human DNA pol ? B
  • Applications tips:
Description: A polyclonal antibody for detection of DNA pol ? B from Human. This DNA pol ? B antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNA pol ? B

DNA pol ? B Polyclonal Antibody

ABP52796-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human DNA pol ? B
  • Applications tips:
Description: A polyclonal antibody for detection of DNA pol ? B from Human. This DNA pol ? B antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNA pol ? B

DNA pol ? B Polyclonal Antibody

ES3795-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against DNA pol ? B from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

DNA pol ? B Polyclonal Antibody

ES3795-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against DNA pol ? B from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Recombinant Succinate Dehydrogenase Complex Subunit B (SDHB)

4-RPJ756Hu01
  • EUR 456.61
  • EUR 225.00
  • EUR 1437.28
  • EUR 545.76
  • EUR 991.52
  • EUR 368.00
  • EUR 3443.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Inquire
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 25.0kDa
  • Isoelectric Point: 8.4
Description: Recombinant Human Succinate Dehydrogenase Complex Subunit B expressed in: E.coli

Recombinant Succinate Dehydrogenase Complex Subunit B (SDHB)

4-RPJ756Mu01
  • EUR 485.28
  • EUR 233.00
  • EUR 1544.80
  • EUR 581.60
  • EUR 1063.20
  • EUR 388.00
  • EUR 3712.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q9CQA3
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 25.0kDa
  • Isoelectric Point: Inquire
Description: Recombinant Mouse Succinate Dehydrogenase Complex Subunit B expressed in: E.coli

Acinetobacter baylyi Catechol 1, 2-dioxygenase (catA)

1-CSB-EP357202AWW
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 50.3 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Acinetobacter baylyi Catechol 1,2-dioxygenase(catA) expressed in E.coli

Acinetobacter baumannii Outer membrane protein Omp38 (omp38)

1-CSB-EP387720AUD
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 52.5 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Acinetobacter baumannii Outer membrane protein Omp38(omp38) expressed in E.coli

Acinetobacter baumannii Outer membrane protein Omp38 (omp38)

1-CSB-YP387720AUD
  • EUR 679.00
  • EUR 335.00
  • EUR 2172.00
  • EUR 1051.00
  • EUR 1442.00
  • EUR 435.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 38.5 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Acinetobacter baumannii Outer membrane protein Omp38(omp38) expressed in Yeast

50-1500bp DNA Marker, Ready-to-use

M109-B 5x100loading, 500prep
EUR 219.65
  • Product category: Electrophoresis Related/Ladders - DNA/50-1500 bp

Fmoc-b-Ala-OH

B-1025.0005 5.0g
EUR 115
Description: Sum Formula: C18H17NO4; CAS# [35737-10-1]

Fmoc-b-Ala-OH

B-1025.0025 25.0g
EUR 236
Description: Sum Formula: C18H17NO4; CAS# [35737-10-1]

Fmoc-b-Ala-OH

B-1025.0100 100.0g
EUR 635
Description: Sum Formula: C18H17NO4; CAS# [35737-10-1]

Fmoc-b-Ala-OPfp

B-1765.0005 5.0g
EUR 236
Description: Sum Formula: C24H16F5NO4; CAS# [149303-38-8]

Fmoc-b-Ala-OPfp

B-1765.0025 25.0g
EUR 841
Description: Sum Formula: C24H16F5NO4; CAS# [149303-38-8]

Recombinant human DNA-directed RNA polymerase III subunit RPC4

P1640 100ug Ask for price
  • Uniprot ID: P05423
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for human DNA-directed RNA polymerase III subunit RPC4

DFFA DNA Fragmentation Factor Subunit Alpha Human Recombinant Protein

PROTO00273 Regular: 25ug
EUR 317
Description: DFFA Human Recombinant fused with 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 351 amino acids (1- 331 a.a.) and having a molecular mass of 38.7kDa.;The DFFA is purified by proprietary chromatographic techniques.

DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) Antibody

20-abx008825
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PK) Antibody

20-abx013061
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) Antibody

abx232474-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Bisphenol A, DNA Aptamer, Biotinylated

AD-108-B Custom Ask for price

Daunomycin (10.10), DNA Aptamer, Biotinylated

AD-113-B Custom Ask for price

Daunomycin (10.10v), DNA Aptamer, Biotinylated

AD-114-B Custom Ask for price

Ethanolamine (14.3), DNA Aptamer, Biotinylated

AD-115-B Custom Ask for price

Hematoporphyrin IX , DNA Aptamer, Biotinylated

AD-117-B Custom Ask for price

Pb(II) , DNA Aptamer, Biotinylated

AD-131-B Custom Ask for price

Ramos Cells , DNA Aptamer, Biotinylated

AD-138-B Custom Ask for price

Streptavidin (31), DNA Aptamer, Biotinylated

AD-144-B Custom Ask for price

Tetracyclines (T24) , DNA Aptamer, Biotinylated

AD-148-B Custom Ask for price

Thrombin(15mer) , DNA Aptamer, Biotinylated

AD-150-B Custom Ask for price

TLR-9, DNA aptamer, Biotinylated

AD-158-B Custom Ask for price

Fmoc-b-cyclopropyl-Ala-OH

B-2905.0001 1.0g
EUR 345
Description: Sum Formula: C21H21NO4; CAS# [214750-76-2]

Fmoc-b-cyclopropyl-Ala-OH

B-2905.0005 5.0g
EUR 1301
Description: Sum Formula: C21H21NO4; CAS# [214750-76-2]

Fmoc-b-cyclohexyl-Ala-OH

B-1975.0001 1.0g
EUR 126
Description: Sum Formula: C24H27NO4; CAS# [135673-97-1]

Fmoc-b-cyclohexyl-Ala-OH

B-1975.0005 5.0g
EUR 418
Description: Sum Formula: C24H27NO4; CAS# [135673-97-1]

Fmoc-b-cyclohexyl-Ala-OH

B-1975.0025 25.0g
EUR 1192
Description: Sum Formula: C24H27NO4; CAS# [135673-97-1]

HCV NS4 recombinant antigen NS4a+b, Biotin

00116-V-B-01mg 0,1 mg
EUR 267.5
  • Category: Antigens, HCV, Ag
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Biotin conjugate.

HCV NS4 recombinant antigen NS4a+b, Biotin

00116-V-B-1000ug 1000 ug
EUR 1282.5
  • Category: Antigens, HCV, Ag
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Biotin conjugate.

Recombinant Chromatin Assembly Factor 1, Subunit B (CHAF1B)

4-RPJ447Mu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q9D0N7
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 26.2kDa
  • Isoelectric Point: Inquire
Description: Recombinant Mouse Chromatin Assembly Factor 1, Subunit B expressed in: E.coli

Recombinant Platelet Derived Growth Factor Subunit B (PDGFB)

4-RPC921Hu01
  • EUR 512.16
  • EUR 240.00
  • EUR 1645.60
  • EUR 615.20
  • EUR 1130.40
  • EUR 406.00
  • EUR 3964.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P01127
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 28.6kDa
  • Isoelectric Point: 9.5
Description: Recombinant Human Platelet Derived Growth Factor Subunit B expressed in: E.coli

Human DNA primase small subunit (PRIM1)

1-CSB-EP018680HU
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 65.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human DNA primase small subunit(PRIM1) expressed in E.coli

Primase (DNA) Subunit 1 (PRIM1) Antibody

20-abx008837
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Primase (DNA) Subunit 1 (PRIM1) Antibody

abx036212-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Primase (DNA) Subunit 1 (PRIM1) Antibody

20-abx014428
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

DNA Fragmentation Factor Subunit alpha Protein

20-abx261772
  • EUR 3766.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 25 ug
  • 5 ug
  • Shipped within 5-10 working days.

DNA Polymerase Catalytic Subunit (BALF5) Antibody

20-abx319917
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Primase (DNA) Subunit 1 (PRIM1) Antibody

abx236776-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Primase (DNA) Subunit 1 (PRIM1) Antibody

abx332539-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Primase (DNA) Subunit 1 (PRIM1) Antibody

20-abx328360
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Primase (DNA) Subunit 1 (PRIM1) Antibody

20-abx301005
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

B-Myb DNA Binding ELISA Kit

abx596661-96tests 96 tests
EUR 754
  • Shipped within 1-2 weeks.

Anti-DNA pol epsilon B antibody

STJ96430 200 µl
EUR 197
Description: Rabbit polyclonal to DNA pol epsilon B.

Recombinant Human DNA Polymerase δ Subunit 2/POLD2 (C-6His)

CF68-10ug 10ug
EUR 202
Description: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Recombinant Human DNA Polymerase δ Subunit 2/POLD2 (C-6His)

CF68-1mg 1mg
EUR 2486
Description: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Recombinant Human DNA Polymerase δ Subunit 2/POLD2 (C-6His)

CF68-500ug 500ug
EUR 1755
Description: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Recombinant Human DNA Polymerase δ Subunit 2/POLD2 (C-6His)

CF68-50ug 50ug
EUR 496
Description: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Abrin Toxin (TA6), DNA Aptamer, Biotinylated

AD-101-B Custom Ask for price

Adenosine/ATP (DH25.42), DNA Aptamer, Biotinylated

AD-104-B Custom Ask for price

CCRF-CEM (SGC8c), DNA Aptamer, Biotinylated

AD-109-B Custom Ask for price

Cellobiose (Cel#16), DNA Aptamer, Biotinylated

AD-110-B Custom Ask for price

Cholic Acid (9), DNA Aptamer, Biotinylated

AD-111-B Custom Ask for price
The genetic range was average (π = 0.00265 and Hd = 0.424) and regarded appropriated for this breeding inhabitants of pacu. Our outcomes present help for the genetic range upkeep and mtDNA traceability of pacu business broodstocks.

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