• April 23, 2021
Mitochondrial genome stability in human: understanding the role of DNA repair pathways

Mitochondrial genome stability in human: understanding the role of DNA repair pathways

Mitochondria are semiautonomous organelles in eukaryotic cells and possess their very own genome that replicates independently. Mitochondria play a significant function in oxidative phosphorylation on account of which its genome is often uncovered to oxidative stress. Components together with ionizing radiation, radiomimetic medication and replication fork stalling also can lead to several types of mutations in mitochondrial DNA (mtDNA) resulting in genome fragility.
Mitochondria from myopathies, dystonia, most cancers affected person samples present frequent mtDNA mutations reminiscent of level mutations, insertions and large-scale deletions that would account for mitochondria-associated illness pathogenesis. The mechanism by which such mutations come up following publicity to numerous DNA-damaging brokers isn’t nicely understood. One of many well-studied restore pathways in mitochondria is base excision restore.
Different restore pathways reminiscent of mismatch restore, homologous recombination and microhomology-mediated finish becoming a member of have additionally been reported. Curiously, nucleotide excision restore and classical nonhomologous DNA finish becoming a member of should not detected in mitochondria. On this assessment, we summarize the potential causes of mitochondrial genome fragility, their implications in addition to numerous DNA restore pathways that function in mitochondria.

Lack of Mitochondrial Protease CLPP Prompts Sort I IFN Responses via the Mitochondrial DNA-cGAS-STING Signaling Axis

Caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) is a serine protease that degrades broken or misfolded mitochondrial proteins. CLPP-null mice exhibit progress retardation, deafness, and sterility, resembling human Perrault syndrome, but additionally show immune system alterations. Nevertheless, the molecular mechanisms and signaling pathways underlying immunological modifications in CLPP-null mice stay unclear.
On this research, we report the steady-state activation of sort I IFN signaling and antiviral gene expression in CLPP-deficient cells and tissues, leading to marked resistance to RNA and DNA virus an infection. Depletion of the cyclic GMP-AMP (cGAS)-stimulator of IFN genes (STING) DNA sensing pathway reduces steady-state IFN-I signaling and abrogates the broad antiviral phenotype of CLPP-null cells. Furthermore, we report that CLPP deficiency results in mitochondrial DNA (mtDNA) instability and packaging alterations.
Pharmacological and genetic approaches to deplete mtDNA or inhibit cytosolic launch markedly scale back antiviral gene expression, implicating mtDNA stress as the driving force of IFN-I signaling in CLPP-null mice. Our work locations the cGAS-STING-IFN-I innate immune pathway downstream of CLPP and should have implications for understanding Perrault syndrome and different human ailments involving CLPP dysregulation.

Mitochondrial DNA from osteoarthritic sufferers drives purposeful impairment of mitochondrial exercise: a research on transmitochondrial cybrids

With the redefinition of osteoarthritis (OA) and the understanding that the joint behaves as an organ, OA is now thought of a systemic sickness with a low grade of power irritation. Mitochondrial dysfunction is nicely documented in OA and has the capability to change chondrocyte and synoviocyte perform. Transmitochondrial cybrids are steered as a helpful mobile mannequin to review mitochondrial biology in vitro, as they carry totally different mitochondrial variants with the identical nuclear background.
The purpose of this work was to review mitochondrial and metabolic perform of cybrids with mitochondrial DNA from wholesome (N) and OA donors. On this work, the authors exhibit that cybrids from OA sufferers behave otherwise from cybrids from N donors in a number of mitochondrial parameters. Moreover, OA cybrids behave equally to OA chondrocytes. These outcomes improve our understanding of the function of mitochondria within the degeneration strategy of OA and current cybrids as a helpful mannequin to review OA pathogenesis.

Mitochondrial DNA permits AIM2 inflammasome activation and hepatocyte pyroptosis in non-alcoholic fatty liver illness

Nonalcoholic fatty liver illness (NAFLD) is typified by accumulating extra liver triacylglycerol, irritation, and liver dysfunction. This research was aimed to analyze the function of mitochondrial DNA synthesis-induced activation of Absent in melanoma 2 (AIM2) inflammasome and pyroptosis in NAFLD. Mice had been raised on a high-fat food plan for 24 weeks to ascertain NAFLD fashions. F4/80 immunofluorescence was carried out to mirror the inflammatory response within the liver of mice. Western blot, ELISA, and immunofluorescence had been adopted to find out the expression of AIM2 inflammasome-related proteins and components.
EdU immunofluorescence was utilized for the examination of mitochondrial DNA expression and circulation cytometry for cell pyroptosis. Agarose gel electrophoresis was used to detect the integrity of extracted mouse mitochondrial DNA (mtDNA). The degrees of AIM2 inflammasome-related proteins within the liver and the degrees of IL-1β and IL-18 in serum had been elevated in high-fat diet-induced NAFLD mice. AIM2 inflammasome activation and pyroptosis had been triggered, and suppressed activation of AIM2 inflammasome alleviated the irritation and pyroptosis within the liver of NAFLD mice. Mitochondria had been severely broken and mtDNA was synthesized after NAFLD modeling.
Mitochondrial genome stability in human: understanding the role of DNA repair pathways
Additional, mtDNA therapy may promote palmitate (PA)-induced activation of AIM2 inflammasome and pyroptosis. Furthermore, inhibition of IRF1 gene alleviated PA-induced AIM2 inflammasome activation and pyroptosis. In conclusion, mitochondrial DNA synthesis may allow AIM2 inflammasome activation and induce the hepatocyte pyroptosis, thereby exacerbating NAFLD.

Haplotypes traceability and genetic variability of the breeding inhabitants of pacu (Piaractus mesopotamicus) revealed by mitochondrial DNA

The principle goal of this research was to estimate the genetic range ranges and haplotype traceability in pacu Piaractus mesopotamicus from the breeding program positioned in Brazil by analyses of the mitochondrial DNA management area (mtDNA). Furthermore, broodstocks from eight business fish farms had been used for comparative analysis, 4 from Brazil (Br1-Br4) and 4 from Argentina (Ar1-Ar4). The descriptive outcomes revealed 47 polymorphic websites and 51 mutations, which evidenced 34 haplotypes. Ten haplotypes had been shared amongst fish farms and 24 had been unique.
The nucleotide range (π) ranged from 0.00031 to 0.01462 and haplotype range (Hd) from 0.125 to 0.868. The evaluation of molecular variance (AMOVA) indicated excessive construction current within the analyzed shares (FST = 0.13356 and ФST = 0.52707). The genetic range was excessive in a lot of the business broodstocks, particularly these from Brazil. We noticed seven haplotypes within the genetic breeding inhabitants, of which 4 had been unique and three shared among the many business fish farms.

S. aureus DNA Gyrase

TG2000GSA-3 500 units
EUR 859.2

S. aureus DNA Gyrase

TG2000GSA-5 1000 units
EUR 1262.4

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (50ug Relaxed DNA + 100u Gyrase)

TG2000G-1KIT 100 assays
EUR 456

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (250ug Relaxed DNA + 500u Gyrase)

TG2000G-3KIT 500 assays
EUR 1182

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (500ug Relaxed DNA + 1000u Gyrase)

TG2000G-5KIT 1000 assays
EUR 1934.4

Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (1mg Relaxed DNA + 2000u Gyrase)

TG2000G-7KIT 2000 assays
EUR 3412.8

Acinetobacter

PVT14723 2 ug
EUR 843.6

Purified E. coli DNA Gyrase Drug Screening Kit (50ug Relaxed DNA + 100u Gyrase)

TG2001G-1KIT 100 assays
EUR 496.8

Purified E. coli DNA Gyrase Drug Screening Kit (250ug Relaxed DNA + 500u Gyrase)

TG2001G-3KIT 500 assays
EUR 1262.4

Purified E. coli DNA Gyrase Drug Screening Kit (500ug Relaxed DNA + 1000u Gyrase)

TG2001G-5KIT 1000 assays
EUR 2203.2

Purified E. coli DNA Gyrase Drug Screening Kit (1mg Relaxed DNA + 2000u Gyrase)

TG2001G-7KIT 2000 assays
EUR 3547.2

E. coli DNA gyrase - for 100 assays

TOP2-100EC 100 assays
EUR 309.4
Description: This product includes wild-type E. coli gyrase for 100 assays (40 ul of 2000 nM stock solution)

P. aeruginosa DNA gyrase - for 100 assays

TOP2-100PA 100 assays
EUR 309.4
Description: This product includes 50 ul of 2 uM P. aeruginosa gyrase

S. aureus DNA gyrase - for 100 assays

TOP2-100SA 100 assays
EUR 309.4
Description: This product includes 43 ul of 7.5 uM S. aureus gyrase.

E. coli DNA Topoisomerase II (Gyrase) Assay Kit Plus (E. coli gyrase included)

DSA020KE 20 assays
EUR 221.78
Description: This product includes160 ul of 10 x Buffer T2, 84 ul of 10 x relaxed DNA, 6 ul of 1500 x H19 dye, 90 ul of 10 x ATP and 550 ul of 10 x H19 dilution buffer. It is for 20 assays in 96-well plate format. E. coli gyrase is not included.

100 BP DNA LADDER, 500UL PER KIT

M-DNA-100BP 1/pk
EUR 87.6
Description: Bioscience Mol Bio; DNA Ladder

1 KB DNA LADDER, 500UL PER KIT

M-DNA-1KB 1/pk
EUR 84
Description: Bioscience Mol Bio; DNA Ladder

S. aureus Gyrase DNA Supercoiling Assay Plus-100

DSA100KSE 100 assays
EUR 681.29
Description: This product includes 500 ul of 10 x Buffer T2, 410 ul of 10 x relaxed DNA, 22 ul of 1500 x H19 dye, 450 ul of 10 x ATP, 43 ul 7.5 uM S. aureus gyrase, 820 ul of 2 M potassium glutamate and 3000 ul of 10 x H19 dilution buffer. It is for 100 assays in a 96-well plate format.

metallo-b-lactamase inhibitor, DNA aptamer, Biotinylated

AD-159-B Custom Ask for price

DNA Topoisomerase II (Gyrase) Assay Kit (enzyme not included)

DSA020K 20 assays
EUR 184.03
Description: This product includes the reaction buffer (T2 Buffer), relaxed plasmid DNA and fluorescence dye H19 for 20 assays of DNA supercoiling reactions a 96-well plate assay format or 40 assays in a 384-well assay format.

Multivalent B-cell receptor specific, DNA apatamer, Biotinylated

AD-156-B Custom Ask for price

Acinetobacter baumannii PCR kit

PCR-H681-48D 50T
EUR 543.6

Acinetobacter baumannii PCR kit

PCR-H681-96D 100T
EUR 686.4

S. aureus Gyrase DNA Supercoiling Assay Kit Plus (enzyme included)

DSA020KSE 20 assays
EUR 240.65
Description: This product includes160 ul of 10 x Buffer T2, 84 ul of 10 x relaxed DNA, 6 ul of 1500 x H19 dye, 90 ul of 10 x ATP, 10 ul 7.5 uM S. aureus gyrase, 180 ul of 2 M potassium glutamate and 550 ul of 10 x H19 dilution buffer. It is for 20 assays in a 96-well plate format.

P. aeruginosa Gyrase DNA Supercoiling Assay Kit Plus (enzyme included)

DSA100KP 100 assays
EUR 590.51
Description: This product includes all the reagents for 100 assays of P. aeruginosa gyrase DNA supercoiling activity. This product includes 600 ul of 10 x Buffer T2, 405 ul of 10 x relaxed DNA, 20 ul of 1500 x H19 dye, 450 ul of 10 x ATP, 3000 ul of 10 x H19 dilution buffer and 50 ul 100 x P. aeruginosa gyrase.

Platelet-Derived Growth Factor B-chain (36t), DNA Aptamer, Biotinylated

AD-136-B Custom Ask for price

Rat Pola2/ DNA polymerase alpha subunit B ELISA Kit

E0777Ra 1 Kit
EUR 775.2

Rat Pola2(DNA polymerase alpha subunit B) ELISA Kit

ER0533 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 18.75pg/ml

Human POLA2/ DNA polymerase alpha subunit B ELISA Kit

E1985Hu 1 Kit
EUR 726

ELISA kit for Rat DNA polymerase alpha subunit B

EK3396 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat DNA polymerase alpha subunit B in samples from serum, plasma, tissue homogenates and other biological fluids.

Human DNA polymerase alpha subunit B, POLA2 ELISA KIT

ELI-26200h 96 Tests
EUR 988.8

Mouse DNA polymerase alpha subunit B, Pola2 ELISA KIT

ELI-26201m 96 Tests
EUR 1038

Bovine DNA polymerase alpha subunit B, POLA2 ELISA KIT

ELI-09178b 96 Tests
EUR 1113.6

Acinetobacter baumannii RT PCR kit

RTq-H681-100D 100T
EUR 860.4

Acinetobacter baumannii RT PCR kit

RTq-H681-150D 150T
EUR 969.6

Acinetobacter baumannii RT PCR kit

RTq-H681-50D 50T
EUR 717.6

Gyrase Assay Buffer 5x

TG4030 1ml
EUR 174

Taq DNA polymerase (TQ21) , DNA Aptamer, Biotinylated

AD-146-B Custom Ask for price

E. coli DNA Topoisomerase II (Gyrase) Assay Kit Plus-100 (enzyme included)

DSA100KE 100 assays
EUR 590.51
Description: This product includes all the reagents for 100 assays of E. coli gyrase DNA supercoiling activity. This product includes 600 ul of 10 x Buffer T2, 405 ul of 10 x relaxed DNA, 20 ul of 1500 x H19 dye, 450 ul of 10 x ATP, 3000 ul of 10 x H19 dilution buffer and 50 ul 100 x E.coli gyrase.

96-well E. coli Gyrase DNA Cleavage Assay Kit Plus (enzyme included)

T2C96KE 96 assays
EUR 597.7
Description: This product includes 300 ul of 10 x reaction buffer, 30 ul of 10 x DNA, 260 ul of SDS solution, 30 ul of 100 mM ATP, 260 ul of proteinase K solutions, 10 ml of TDC matrix, 6 ml of rinse buffer, 500 ul of 10 x dye, a black receiver plate, a V-bottom reaction plate, 26 ul of 100 x E. coli Gyrase and a TDC filter plate. A plate filtration device and a vacuum line are needed for the plate filtration process.

96-Well E. coli gyrase DNA Decatenation Assay Kit Plus (enzyme included)

T2DD-96KE 96 assays
EUR 591.41
Description: This product includes the assay buffer, concatenated DNA, E. coli gyrase, ATP, fluorescence dye, rinse buffer and a TDD filter plate for 96 assays of E. coli gyrase DNA decatenation reactions.

96-Well S. aureus gyrase DNA Decatenation Assay Kit Plus (enzyme included)

T2DD-96KS 96 assays
EUR 681.29
Description: This product includes 600 ul of 10 x assay buffer, 500 ul of 10 x concatenated DNA, 120 ul of 10 mM ATP, 100 ul of 50 x S. aureus gyrase, 600 ul of Stop solution (0.4 M EDTA), 500 ul of 10 x fluorescence dye, 2 ml of 10 x rinse buffer, one V-bottom plate, a TDD filter plate and one black 96-well plates for 96 assays of DNA decatenation reactions.

Recombinant Human DNA Fragmentation Factor Subunit Alpha

7-04978 5µg Ask for price

Recombinant Human DNA Fragmentation Factor Subunit Alpha

7-04979 25µg Ask for price

Recombinant Human DNA Fragmentation Factor Subunit Alpha

7-04980 1mg Ask for price

DNA Polymerase Delta Subunit 2 Recombinant Protein

92-121 0.05 mg
EUR 852.9
Description: DNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta/II small subunit family. POLD2 can form a heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. POLD2 possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. POLD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA).

Recombinant human DNA polymerase delta subunit 2

P2733 100ug Ask for price
Description: Recombinant protein for human DNA polymerase delta subunit 2

Recombinant human DNA polymerase subunit gamma-1

P2838 100ug Ask for price
Description: Recombinant protein for human DNA polymerase subunit gamma-1

Recombinant DNA Fragmentation Factor Subunit Alpha (DFFa)

4-RPL426Hu01
  • EUR 599.54
  • EUR 283.20
  • EUR 1918.27
  • EUR 719.42
  • EUR 1318.85
  • EUR 476.40
  • EUR 4615.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human DNA Fragmentation Factor Subunit Alpha expressed in: E.coli

Recombinant DNA Fragmentation Factor Subunit Alpha (DFFa)

4-RPL426Mu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse DNA Fragmentation Factor Subunit Alpha expressed in: E.coli

Fmoc-b,b-diphenyl-Ala-OH

B-2725.0250 250.0mg
EUR 166.8
Description: Sum Formula: C30H25NO4; CAS# [201484-50-6]

Fmoc-b,b-diphenyl-Ala-OH

B-2725.1000 1.0g
EUR 428.4
Description: Sum Formula: C30H25NO4; CAS# [201484-50-6]

Fmoc-b,b-diphenyl-Ala-OH

B-2725.5000 5.0g
EUR 1603.2
Description: Sum Formula: C30H25NO4; CAS# [201484-50-6]

Acinetobacter baumannii Beta-lactamase (NDM-1)

1-CSB-RP076174Ba
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Acinetobacter baumannii Beta-lactamase(NDM-1),partial expressed in E.coli

Acinetobacter baumannii Elongation factor Tu (tuf1)

1-CSB-EP025342AUD
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Acinetobacter baumannii Elongation factor Tu(tuf1) expressed in E.coli

Acinetobacter calcoaceticus Catechol 1, 2-dioxygenase

1-CSB-EP306913AWR
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Acinetobacter calcoaceticus Catechol 1,2-dioxygenase expressed in E.coli

Acinetobacter baumannii Elongation factor Tu (tuf1)

1-CSB-YP025342AUD
  • EUR 814.80
  • EUR 402.00
  • EUR 2606.40
  • EUR 1261.20
  • EUR 1730.40
  • EUR 522.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Acinetobacter baumannii Elongation factor Tu(tuf1) expressed in Yeast

Acinetobacter baumannii One-Step PCR kit

Oneq-H681-100D 100T
EUR 1039.2

Acinetobacter baumannii One-Step PCR kit

Oneq-H681-150D 150T
EUR 1177.2

Acinetobacter baumannii One-Step PCR kit

Oneq-H681-50D 50T
EUR 861.6

Human Neutrophil Elastase (DNA I) , DNA Aptamer, Biotinylated

AD-155-B Custom Ask for price

5X SA Gyrase Assay Buffer

TG4045 1ml
EUR 187.2

Pola2 ELISA Kit| Rat DNA polymerase alpha subunit B ELISA Kit

EF017366 96 Tests
EUR 826.8

Phenolics Mix B

8040-B 1ML
EUR 61.56

Analyte Mix B

507-B 1ML
EUR 182.4

Analyte Mix B

5081-B 1ML
EUR 129.96

DNA pol ? B Polyclonal Antibody

ABP52796-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of DNA pol ? B from Human. This DNA pol ? B antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNA pol ? B

DNA pol ? B Polyclonal Antibody

ABP52796-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of DNA pol ? B from Human. This DNA pol ? B antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNA pol ? B

DNA pol ? B Polyclonal Antibody

ABP52796-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of DNA pol ? B from Human. This DNA pol ? B antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNA pol ? B

DNA Helicase B (HELB) Antibody

abx233821-100ug 100 ug
EUR 661.2

DNA pol ? B Polyclonal Antibody

ES3795-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against DNA pol ? B from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

DNA pol ? B Polyclonal Antibody

ES3795-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against DNA pol ? B from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Adenosine, DNA Aptamer, Biotinylated

AD-103-B Custom Ask for price

Acinetobacter baylyi Catechol 1, 2-dioxygenase (catA)

1-CSB-EP357202AWW
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Acinetobacter baylyi Catechol 1,2-dioxygenase(catA) expressed in E.coli

Acinetobacter baumannii Outer membrane protein Omp38 (omp38)

1-CSB-EP387720AUD
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Acinetobacter baumannii Outer membrane protein Omp38(omp38) expressed in E.coli

Acinetobacter baumannii Outer membrane protein Omp38 (omp38)

1-CSB-YP387720AUD
  • EUR 814.80
  • EUR 402.00
  • EUR 2606.40
  • EUR 1261.20
  • EUR 1730.40
  • EUR 522.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Acinetobacter baumannii Outer membrane protein Omp38(omp38) expressed in Yeast

50-1500bp DNA Marker, Ready-to-use

M109-B 5x100loading, 500prep
EUR 263.58

DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) Antibody

20-abx008825
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PK) Antibody

20-abx013061
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) Antibody

abx232474-100ug 100 ug
EUR 610.8

Fmoc-b-Ala-OPfp

B-1765.0005 5.0g
EUR 283.2
Description: Sum Formula: C24H16F5NO4; CAS# [149303-38-8]

Fmoc-b-Ala-OPfp

B-1765.0025 25.0g
EUR 1009.2
Description: Sum Formula: C24H16F5NO4; CAS# [149303-38-8]

Fmoc-b-Ala-OH

B-1025.0005 5.0g
EUR 138
Description: Sum Formula: C18H17NO4; CAS# [35737-10-1]

Fmoc-b-Ala-OH

B-1025.0025 25.0g
EUR 283.2
Description: Sum Formula: C18H17NO4; CAS# [35737-10-1]

Fmoc-b-Ala-OH

B-1025.0100 100.0g
EUR 762
Description: Sum Formula: C18H17NO4; CAS# [35737-10-1]

Purgeable Gases Mix B

624-B 1ML
EUR 249.66

Purgeable Gases Mix B

5022-B 1ML
EUR 27.36

Calcineurin Subunit B Type 1 Recombinant Protein

92-008 0.05 mg
EUR 821.4
Description: Calcineurin Subunit B Type 1 belongs to the calcineurin regulatory subunit family. Calcineurin Subunit B Type 1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase. It is composed of a catalytic subunit (A) and a regulatory subunit (B). It contains four EF-hand domains and four functional calcium-binding sites. Calcineurin Subunit B Type 1 plays an improtant role in the T cell activation pathway.

Recombinant Succinate Dehydrogenase Complex Subunit B (SDHB)

4-RPJ756Hu01
  • EUR 547.93
  • EUR 270.00
  • EUR 1724.74
  • EUR 654.91
  • EUR 1189.82
  • EUR 441.60
  • EUR 4131.84
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Succinate Dehydrogenase Complex Subunit B expressed in: E.coli

Recombinant Succinate Dehydrogenase Complex Subunit B (SDHB)

4-RPJ756Mu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Succinate Dehydrogenase Complex Subunit B expressed in: E.coli

Recombinant DNA-directed RNA polymerase 132 kDa polypeptide(RPO132) ,partial

CSB-EP851803MHV-B 20μg Ask for price
Description: In Vivo Biotinylation in E.coli

Bisphenol A, DNA Aptamer, Biotinylated

AD-108-B Custom Ask for price

Daunomycin (10.10), DNA Aptamer, Biotinylated

AD-113-B Custom Ask for price

Daunomycin (10.10v), DNA Aptamer, Biotinylated

AD-114-B Custom Ask for price

Ethanolamine (14.3), DNA Aptamer, Biotinylated

AD-115-B Custom Ask for price

Hematoporphyrin IX , DNA Aptamer, Biotinylated

AD-117-B Custom Ask for price

Pb(II) , DNA Aptamer, Biotinylated

AD-131-B Custom Ask for price

Ramos Cells , DNA Aptamer, Biotinylated

AD-138-B Custom Ask for price

Streptavidin (31), DNA Aptamer, Biotinylated

AD-144-B Custom Ask for price

Tetracyclines (T24) , DNA Aptamer, Biotinylated

AD-148-B Custom Ask for price

Thrombin(15mer) , DNA Aptamer, Biotinylated

AD-150-B Custom Ask for price

TLR-9, DNA aptamer, Biotinylated

AD-158-B Custom Ask for price

Recombinant human DNA-directed RNA polymerase III subunit RPC4

P1640 100ug Ask for price
Description: Recombinant protein for human DNA-directed RNA polymerase III subunit RPC4

DFFA DNA Fragmentation Factor Subunit Alpha Human Recombinant Protein

PROTO00273 Regular: 25ug
EUR 380.4
Description: DFFA Human Recombinant fused with 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 351 amino acids (1- 331 a.a.) and having a molecular mass of 38.7kDa.;The DFFA is purified by proprietary chromatographic techniques.

Recombinant Intermediate transcription factor 3 large subunit(VITF3L)

CSB-EP823719MHV-B 20μg Ask for price
Description: In Vivo Biotinylation in E.coli

Primase (DNA) Subunit 1 (PRIM1) Antibody

20-abx008837
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Primase (DNA) Subunit 1 (PRIM1) Antibody

20-abx014428
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Primase (DNA) Subunit 1 (PRIM1) Antibody

abx036212-100ug 100 ug
EUR 469.2

DNA Polymerase Catalytic Subunit (BALF5) Antibody

20-abx319917
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Primase (DNA) Subunit 1 (PRIM1) Antibody

abx332539-100ul 100 ul
EUR 510

Primase (DNA) Subunit 1 (PRIM1) Antibody

20-abx301005
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Fragmentation Factor Subunit alpha Protein

20-abx261772
  • EUR 4519.20
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Primase (DNA) Subunit 1 (PRIM1) Antibody

20-abx328360
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Primase (DNA) Subunit 1 (PRIM1) Antibody

abx236776-100ug 100 ug
EUR 577.2

Human DNA primase small subunit (PRIM1)

1-CSB-EP018680HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human DNA primase small subunit(PRIM1) expressed in E.coli

Fmoc-b-cyclohexyl-Ala-OH

B-1975.0001 1.0g
EUR 151.2
Description: Sum Formula: C24H27NO4; CAS# [135673-97-1]
The genetic range was average (π = 0.00265 and Hd = 0.424) and regarded appropriated for this breeding inhabitants of pacu. Our outcomes present help for the genetic range upkeep and mtDNA traceability of pacu business broodstocks.

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