Mitochondrial genome stability in human: understanding the role of DNA repair pathways
- Ellie
- 0
Mitochondria are semiautonomous organelles in eukaryotic cells and possess their very own genome that replicates independently. Mitochondria play a significant function in oxidative phosphorylation on account of which its genome is often uncovered to oxidative stress. Components together with ionizing radiation, radiomimetic medication and replication fork stalling also can lead to several types of mutations in mitochondrial DNA (mtDNA) resulting in genome fragility.
Mitochondria from myopathies, dystonia, most cancers affected person samples present frequent mtDNA mutations reminiscent of level mutations, insertions and large-scale deletions that would account for mitochondria-associated illness pathogenesis. The mechanism by which such mutations come up following publicity to numerous DNA-damaging brokers isn’t nicely understood. One of many well-studied restore pathways in mitochondria is base excision restore.
Different restore pathways reminiscent of mismatch restore, homologous recombination and microhomology-mediated finish becoming a member of have additionally been reported. Curiously, nucleotide excision restore and classical nonhomologous DNA finish becoming a member of should not detected in mitochondria. On this assessment, we summarize the potential causes of mitochondrial genome fragility, their implications in addition to numerous DNA restore pathways that function in mitochondria.
Lack of Mitochondrial Protease CLPP Prompts Sort I IFN Responses via the Mitochondrial DNA-cGAS-STING Signaling Axis
Caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) is a serine protease that degrades broken or misfolded mitochondrial proteins. CLPP-null mice exhibit progress retardation, deafness, and sterility, resembling human Perrault syndrome, but additionally show immune system alterations. Nevertheless, the molecular mechanisms and signaling pathways underlying immunological modifications in CLPP-null mice stay unclear.
On this research, we report the steady-state activation of sort I IFN signaling and antiviral gene expression in CLPP-deficient cells and tissues, leading to marked resistance to RNA and DNA virus an infection. Depletion of the cyclic GMP-AMP (cGAS)-stimulator of IFN genes (STING) DNA sensing pathway reduces steady-state IFN-I signaling and abrogates the broad antiviral phenotype of CLPP-null cells. Furthermore, we report that CLPP deficiency results in mitochondrial DNA (mtDNA) instability and packaging alterations.
Pharmacological and genetic approaches to deplete mtDNA or inhibit cytosolic launch markedly scale back antiviral gene expression, implicating mtDNA stress as the driving force of IFN-I signaling in CLPP-null mice. Our work locations the cGAS-STING-IFN-I innate immune pathway downstream of CLPP and should have implications for understanding Perrault syndrome and different human ailments involving CLPP dysregulation.
Mitochondrial DNA from osteoarthritic sufferers drives purposeful impairment of mitochondrial exercise: a research on transmitochondrial cybrids
With the redefinition of osteoarthritis (OA) and the understanding that the joint behaves as an organ, OA is now thought of a systemic sickness with a low grade of power irritation. Mitochondrial dysfunction is nicely documented in OA and has the capability to change chondrocyte and synoviocyte perform. Transmitochondrial cybrids are steered as a helpful mobile mannequin to review mitochondrial biology in vitro, as they carry totally different mitochondrial variants with the identical nuclear background.
The purpose of this work was to review mitochondrial and metabolic perform of cybrids with mitochondrial DNA from wholesome (N) and OA donors. On this work, the authors exhibit that cybrids from OA sufferers behave otherwise from cybrids from N donors in a number of mitochondrial parameters. Moreover, OA cybrids behave equally to OA chondrocytes. These outcomes improve our understanding of the function of mitochondria within the degeneration strategy of OA and current cybrids as a helpful mannequin to review OA pathogenesis.
Mitochondrial DNA permits AIM2 inflammasome activation and hepatocyte pyroptosis in non-alcoholic fatty liver illness
Nonalcoholic fatty liver illness (NAFLD) is typified by accumulating extra liver triacylglycerol, irritation, and liver dysfunction. This research was aimed to analyze the function of mitochondrial DNA synthesis-induced activation of Absent in melanoma 2 (AIM2) inflammasome and pyroptosis in NAFLD. Mice had been raised on a high-fat food plan for 24 weeks to ascertain NAFLD fashions. F4/80 immunofluorescence was carried out to mirror the inflammatory response within the liver of mice. Western blot, ELISA, and immunofluorescence had been adopted to find out the expression of AIM2 inflammasome-related proteins and components.
EdU immunofluorescence was utilized for the examination of mitochondrial DNA expression and circulation cytometry for cell pyroptosis. Agarose gel electrophoresis was used to detect the integrity of extracted mouse mitochondrial DNA (mtDNA). The degrees of AIM2 inflammasome-related proteins within the liver and the degrees of IL-1β and IL-18 in serum had been elevated in high-fat diet-induced NAFLD mice. AIM2 inflammasome activation and pyroptosis had been triggered, and suppressed activation of AIM2 inflammasome alleviated the irritation and pyroptosis within the liver of NAFLD mice. Mitochondria had been severely broken and mtDNA was synthesized after NAFLD modeling.
Additional, mtDNA therapy may promote palmitate (PA)-induced activation of AIM2 inflammasome and pyroptosis. Furthermore, inhibition of IRF1 gene alleviated PA-induced AIM2 inflammasome activation and pyroptosis. In conclusion, mitochondrial DNA synthesis may allow AIM2 inflammasome activation and induce the hepatocyte pyroptosis, thereby exacerbating NAFLD.
Haplotypes traceability and genetic variability of the breeding inhabitants of pacu (Piaractus mesopotamicus) revealed by mitochondrial DNA
The principle goal of this research was to estimate the genetic range ranges and haplotype traceability in pacu Piaractus mesopotamicus from the breeding program positioned in Brazil by analyses of the mitochondrial DNA management area (mtDNA). Furthermore, broodstocks from eight business fish farms had been used for comparative analysis, 4 from Brazil (Br1-Br4) and 4 from Argentina (Ar1-Ar4). The descriptive outcomes revealed 47 polymorphic websites and 51 mutations, which evidenced 34 haplotypes. Ten haplotypes had been shared amongst fish farms and 24 had been unique.
The nucleotide range (π) ranged from 0.00031 to 0.01462 and haplotype range (Hd) from 0.125 to 0.868. The evaluation of molecular variance (AMOVA) indicated excessive construction current within the analyzed shares (FST = 0.13356 and ФST = 0.52707). The genetic range was excessive in a lot of the business broodstocks, particularly these from Brazil. We noticed seven haplotypes within the genetic breeding inhabitants, of which 4 had been unique and three shared among the many business fish farms.
Recombinant Acinetobacter baumannii BlaNDM-1 (NDM-1) ,partial |
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RPC20187-1mg | Biomatik Corporation | 1mg | EUR 2884.7 |
Recombinant Acinetobacter baumannii BlaNDM-1 (NDM-1) ,partial |
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RPC20187-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Recombinant Acinetobacter baylyi Catechol 1,2-dioxygenase(catA) |
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AP74029 | SAB | 1mg | EUR 2826 |
Recombinant Acinetobacter baylyi Catechol 1,2-dioxygenase (catA) |
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CSB-EP357202AWW | Cusabio | 3255 mg | Ask for price |
Recombinant Acinetobacter baylyi Catechol 1,2-dioxygenase (catA) |
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RPC20376-100ug | Biomatik Corporation | 100ug | EUR 721.6 |
Recombinant Acinetobacter baylyi Catechol 1,2-dioxygenase (catA) |
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RPC20376-1mg | Biomatik Corporation | 1mg | EUR 2884.7 |
Recombinant Acinetobacter baylyi Catechol 1,2-dioxygenase (catA) |
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RPC20376-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
OPCA04439-1MG - CATA Recombinant Protein (Acinetobacter baylyi ) |
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OPCA04439-1MG | Aviva Systems Biology | 1mg | EUR 1977 |
Recombinant Acinetobacter calcoaceticus Catechol 1,2-dioxygenase |
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AP77940 | SAB | 1mg | EUR 2826 |
Recombinant Acinetobacter calcoaceticus Catechol 1,2-dioxygenase |
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CSB-EP306913AWR | Cusabio | 2659 mg | Ask for price |
OPCA04439-100UG - CATA Recombinant Protein (Acinetobacter baylyi ) |
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OPCA04439-100UG | Aviva Systems Biology | 100ug | EUR 586 |
OPCA04439-20UG - CATA Recombinant Protein (Acinetobacter baylyi ) |
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OPCA04439-20UG | Aviva Systems Biology | 20ug | EUR 400 |
Recombinant Acinetobacter baumannii Beta-lactamase(NDM-1),partial |
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AP71982 | SAB | 1mg | EUR 2826 |
ACINETOBACTER BAUMANNII GENOMIC DNA |
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MBT122-250R | EWC Diagnostics | 1 unit | EUR 167.43 |
Description: ACINETOBACTER BAUMANNII GENOMIC DNA |
Recombinant Acinetobacter baumannii Outer membrane protein Omp38 (omp38) |
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CSB-YP387720AUD | Cusabio | 6421 mg | Ask for price |
Recombinant Acinetobacter baumannii Outer membrane protein Omp38(omp38) |
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AP71199 | SAB | 1mg | EUR 2826 |
Recombinant Acinetobacter baumannii Outer membrane protein Omp38(omp38) |
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AP73743 | SAB | each | Ask for price |
Recombinant Acinetobacter baumannii Outer membrane protein Omp38 (omp38) |
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CSB-EP387720AUD | Cusabio | 3506 mg | Ask for price |
Recombinant Acinetobacter baumannii Outer membrane protein Omp38 (omp38) |
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CSB-EP754340ABS | Cusabio | 10492 mg | Ask for price |
Recombinant Acinetobacter baumannii Outer membrane protein Omp38 (omp38) |
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RPC22834-100ug | Biomatik Corporation | 100ug | EUR 721.6 |
Recombinant Acinetobacter baumannii Outer membrane protein Omp38 (omp38) |
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RPC22834-1mg | Biomatik Corporation | 1mg | EUR 2884.7 |
Recombinant Acinetobacter baumannii Outer membrane protein Omp38 (omp38) |
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RPC22834-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
OPCA00711-1MG - NDM-1 Recombinant Protein (Acinetobacter baumannii) |
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OPCA00711-1MG | Aviva Systems Biology | 1mg | EUR 2469 |
OPCA00711-100UG - NDM-1 Recombinant Protein (Acinetobacter baumannii) |
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OPCA00711-100UG | Aviva Systems Biology | 100ug | EUR 729 |
Recombinant Acinetobacter baumannii 29 kDa outer membrane protein, partial |
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CSB-EP306078ABS | Cusabio | 2654 mg | Ask for price |
Recombinant Acinetobacter baumannii 29 kDa outer membrane protein,partial |
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RPC27581-100ug | Biomatik Corporation | 100ug | EUR 801.9 |
Recombinant Acinetobacter baumannii 29 kDa outer membrane protein,partial |
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RPC27581-1mg | Biomatik Corporation | 1mg | EUR 2885.2 |
Recombinant Acinetobacter baumannii 29 kDa outer membrane protein,partial |
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RPC27581-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Acinetobacter |
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PVT14723 | Lifescience Market | 2 ug | EUR 843.6 |
Recombinant Acinetobacter baumannii Efflux pump membrane transporter (HMPREF0010_00594) |
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CSB-CF4780GTJ | Cusabio | 11251 mg | Ask for price |
Acinetobacter species |
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5202 | Virostat | each | EUR 270 |
Description: OmpA |
Recombinant Acinetobacter baumannii UDP-3-O-acyl-N-acetylglucosamine deacetylase (lpxC) |
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CSB-EP460177AWO | Cusabio | 3545 mg | Ask for price |
Recombinant Acinetobacter baumannii UDP-3-O-acyl-N-acetylglucosamine deacetylase (lpxC) |
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CSB-EP460177AWOe1 | Cusabio | 3546 mg | Ask for price |
Recombinant Acinetobacter baumannii UDP-3-O-acyl-N-acetylglucosamine deacetylase (lpxC) |
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RPC27323-100ug | Biomatik Corporation | 100ug | EUR 801.9 |
Recombinant Acinetobacter baumannii UDP-3-O-acyl-N-acetylglucosamine deacetylase (lpxC) |
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RPC27323-1mg | Biomatik Corporation | 1mg | EUR 2885.2 |
Recombinant Acinetobacter baumannii UDP-3-O-acyl-N-acetylglucosamine deacetylase (lpxC) |
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RPC27323-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Leeds Acinetobacter Agar Base |
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M1839-100G | EWC Diagnostics | 1 unit | EUR 12.21 |
Description: Leeds Acinetobacter Agar Base |
Leeds Acinetobacter Agar Base |
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M1839-500G | EWC Diagnostics | 1 unit | EUR 57.13 |
Description: Leeds Acinetobacter Agar Base |
Acinetobacter baumannii PCR kit |
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PCR-H681-48D | Bioingentech | 50T | EUR 543.6 |
Acinetobacter baumannii PCR kit |
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PCR-H681-96D | Bioingentech | 100T | EUR 686.4 |
Hicrome Acinetobacter Agar Base |
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M1938-100G | EWC Diagnostics | 1 unit | EUR 116.45 |
Description: Hicrome Acinetobacter Agar Base |
Hicrome Acinetobacter Agar Base |
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M1938-500G | EWC Diagnostics | 1 unit | EUR 556.49 |
Description: Hicrome Acinetobacter Agar Base |
Acinetobacter baumannii RT PCR kit |
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RTq-H681-100D | Bioingentech | 100T | EUR 860.4 |
Acinetobacter baumannii RT PCR kit |
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RTq-H681-150D | Bioingentech | 150T | EUR 969.6 |
Acinetobacter baumannii RT PCR kit |
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RTq-H681-50D | Bioingentech | 50T | EUR 717.6 |
MDR Acinetobacter Selective Supplement |
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FD271-5VL | EWC Diagnostics | 1 unit | EUR 34.57 |
Description: MDR Acinetobacter Selective Supplement |
Leeds Acinetobacter Selective Supplement |
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FD335-5VL | EWC Diagnostics | 1 unit | EUR 28.64 |
Description: Leeds Acinetobacter Selective Supplement |
Acinetobacter baumannii One-Step PCR kit |
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Oneq-H681-100D | Bioingentech | 100T | EUR 1039.2 |
Acinetobacter baumannii One-Step PCR kit |
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Oneq-H681-150D | Bioingentech | 150T | EUR 1177.2 |
Acinetobacter baumannii One-Step PCR kit |
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Oneq-H681-50D | Bioingentech | 50T | EUR 861.6 |
Recombinant Salmonella typhi DNA gyrase subunit B (gyrB), partial |
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CSB-EP358232SWW | Cusabio | 7025 mg | Ask for price |
Recombinant Salmonella typhi DNA gyrase subunit B (gyrB) ,partial |
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RPC27665-100ug | Biomatik Corporation | 100ug | EUR 801.9 |
Recombinant Salmonella typhi DNA gyrase subunit B (gyrB) ,partial |
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RPC27665-1mg | Biomatik Corporation | 1mg | EUR 2885.2 |
Recombinant Salmonella typhi DNA gyrase subunit B (gyrB) ,partial |
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RPC27665-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Hi-PCR® Acinetobacter baumanni SYBr PCR |
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MBPCR065-10R | EWC Diagnostics | 1 unit | EUR 46.44 |
Description: Hi-PCR® Acinetobacter baumanni SYBr PCR |
Hi-PCR® Acinetobacter baumanni SYBr PCR |
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MBPCR065-50R | EWC Diagnostics | 1 unit | EUR 172.71 |
Description: Hi-PCR® Acinetobacter baumanni SYBr PCR |
Hi-PCR® Palm Acinetobacter baumanni Dete |
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MBPCR066-50R | EWC Diagnostics | 1 unit | EUR 102.22 |
Description: Hi-PCR® Palm Acinetobacter baumanni Dete |
genesig Easy kit for Acinetobacter baumannii |
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Z-Path-A.baumannii-EASY | Novacyt Group | 50 tests | EUR 410 |
Description: A.baumannii |
Hi-PCR® Acinetobacter baumanni Semi-Q PC |
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MBPCR038-10R | EWC Diagnostics | 1 unit | EUR 36.46 |
Description: Hi-PCR® Acinetobacter baumanni Semi-Q PC |
Hi-PCR® Acinetobacter baumanni Semi-Q PC |
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MBPCR038-50R | EWC Diagnostics | 1 unit | EUR 145.82 |
Description: Hi-PCR® Acinetobacter baumanni Semi-Q PC |
Recombinant Escherichia coli DNA gyrase subunit A (gyrA) |
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CSB-EP365190ENV(A4M1) | Cusabio | 3448 mg | Ask for price |
Recombinant Escherichia coli DNA gyrase subunit A (gyrA) |
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CSB-EP365190ENV(A4M2) | Cusabio | 3449 mg | Ask for price |
Recombinant Escherichia coli DNA gyrase subunit A (gyrA) |
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RPC27318-100ug | Biomatik Corporation | 100ug | EUR 801.9 |
Recombinant Escherichia coli DNA gyrase subunit A (gyrA) |
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RPC27318-1mg | Biomatik Corporation | 1mg | EUR 2885.2 |
Recombinant Escherichia coli DNA gyrase subunit A (gyrA) |
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RPC27318-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Recombinant Escherichia coli DNA gyrase subunit A (gyrA) |
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RPC27685-100ug | Biomatik Corporation | 100ug | EUR 801.9 |
Recombinant Escherichia coli DNA gyrase subunit A (gyrA) |
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RPC27685-1mg | Biomatik Corporation | 1mg | EUR 2885.2 |
Recombinant Escherichia coli DNA gyrase subunit A (gyrA) |
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RPC27685-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Acinetobacter baumannii Beta-lactamase (NDM-1) |
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1-CSB-RP076174Ba | Cusabio |
|
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Description: Recombinant Acinetobacter baumannii Beta-lactamase(NDM-1),partial expressed in E.coli |
Acinetobacter baumannii Elongation factor Tu (tuf1) |
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1-CSB-YP025342AUD | Cusabio |
|
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Description: Recombinant Acinetobacter baumannii Elongation factor Tu(tuf1) expressed in Yeast |
Acinetobacter baumannii Elongation factor Tu (tuf1) |
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1-CSB-EP025342AUD | Cusabio |
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Description: Recombinant Acinetobacter baumannii Elongation factor Tu(tuf1) expressed in E.coli |
ViPrimePLUS Acinetobacter baumannii qPCR Kit, 150rxns |
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QM2001 | Vivantis | each | Ask for price |
Acinetobacter baylyi Catechol 1, 2-dioxygenase (catA) |
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1-CSB-EP357202AWW | Cusabio |
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Description: Recombinant Acinetobacter baylyi Catechol 1,2-dioxygenase(catA) expressed in E.coli |
Acinetobacter calcoaceticus Catechol 1, 2-dioxygenase |
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1-CSB-EP306913AWR | Cusabio |
|
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Description: Recombinant Acinetobacter calcoaceticus Catechol 1,2-dioxygenase expressed in E.coli |
Acinetobacter baumannii Outer membrane protein Omp38 (omp38) |
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1-CSB-YP387720AUD | Cusabio |
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Description: Recombinant Acinetobacter baumannii Outer membrane protein Omp38(omp38) expressed in Yeast |
Acinetobacter baumannii Outer membrane protein Omp38 (omp38) |
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1-CSB-EP387720AUD | Cusabio |
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Description: Recombinant Acinetobacter baumannii Outer membrane protein Omp38(omp38) expressed in E.coli |
QPCR Kit DNA Acinetobact - EACH |
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MOL6766 | Scientific Laboratory Supplies | EACH | EUR 1176.51 |
QPCR Kit DNA Acinetobact Mmix - EACH |
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MOL6768 | Scientific Laboratory Supplies | EACH | EUR 1499.64 |
DNA gyrase B-IN-1 |
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T64012-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: DNA gyrase B-IN-1 |
DNA gyrase B-IN-1 |
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T64012-1g | TargetMol Chemicals | 1g | Ask for price |
Description: DNA gyrase B-IN-1 |
DNA gyrase B-IN-1 |
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T64012-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: DNA gyrase B-IN-1 |
DNA gyrase B-IN-1 |
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T64012-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: DNA gyrase B-IN-1 |
DNA gyrase B-IN-1 |
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T64012-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: DNA gyrase B-IN-1 |
Recombinant Aquifex aeolicus Reverse gyrase 2 (rgy2), partial |
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CSB-EP524126DNV | Cusabio | 10688 mg | Ask for price |
E. coli DNA Gyrase |
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TG2000G-1 | TopoGen | 100 units | EUR 388.8 |
E. coli DNA Gyrase |
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TG2000G-3 | TopoGen | 500 units | EUR 846 |
E. coli DNA Gyrase |
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TG2000G-5 | TopoGen | 1000 units | EUR 1396.8 |
E. coli DNA Gyrase |
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TG2000G-7 | TopoGen | 2000 units | EUR 2203.2 |
DNA Gyrase-IN-5 |
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T63395-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: DNA Gyrase-IN-5 |
DNA Gyrase-IN-5 |
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T63395-1g | TargetMol Chemicals | 1g | Ask for price |
Description: DNA Gyrase-IN-5 |
DNA Gyrase-IN-5 |
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T63395-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: DNA Gyrase-IN-5 |
DNA Gyrase-IN-5 |
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T63395-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: DNA Gyrase-IN-5 |
DNA Gyrase-IN-5 |
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T63395-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: DNA Gyrase-IN-5 |
DNA Gyrase-IN-4 |
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T62895-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: DNA Gyrase-IN-4 |
DNA Gyrase-IN-4 |
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T62895-1g | TargetMol Chemicals | 1g | Ask for price |
Description: DNA Gyrase-IN-4 |
DNA Gyrase-IN-4 |
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T62895-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: DNA Gyrase-IN-4 |
DNA Gyrase-IN-4 |
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T62895-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: DNA Gyrase-IN-4 |
DNA Gyrase-IN-4 |
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T62895-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: DNA Gyrase-IN-4 |
DNA Gyrase-IN-3 |
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T61937-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: DNA Gyrase-IN-3 |
DNA Gyrase-IN-3 |
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T61937-1g | TargetMol Chemicals | 1g | Ask for price |
Description: DNA Gyrase-IN-3 |
DNA Gyrase-IN-3 |
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T61937-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: DNA Gyrase-IN-3 |
DNA Gyrase-IN-3 |
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T61937-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: DNA Gyrase-IN-3 |
DNA Gyrase-IN-3 |
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T61937-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: DNA Gyrase-IN-3 |
DNA Gyrase-IN-2 |
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T63442-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: DNA Gyrase-IN-2 |
DNA Gyrase-IN-2 |
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T63442-1g | TargetMol Chemicals | 1g | Ask for price |
Description: DNA Gyrase-IN-2 |
DNA Gyrase-IN-2 |
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T63442-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: DNA Gyrase-IN-2 |
DNA Gyrase-IN-2 |
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T63442-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: DNA Gyrase-IN-2 |
DNA Gyrase-IN-2 |
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T63442-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: DNA Gyrase-IN-2 |
DNA Gyrase-IN-1 |
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T63681-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: DNA Gyrase-IN-1 |
DNA Gyrase-IN-1 |
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T63681-1g | TargetMol Chemicals | 1g | Ask for price |
Description: DNA Gyrase-IN-1 |
DNA Gyrase-IN-1 |
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T63681-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: DNA Gyrase-IN-1 |
DNA Gyrase-IN-1 |
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T63681-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: DNA Gyrase-IN-1 |
DNA Gyrase-IN-1 |
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T63681-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: DNA Gyrase-IN-1 |
DNA Gyrase Assay Kit |
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TG1003 | TopoGen | 100 assays | EUR 375.6 |
S. aureus DNA Gyrase |
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TG2000GSA-1 | TopoGen | 100 units | EUR 483.6 |
S. aureus DNA Gyrase |
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TG2000GSA-3 | TopoGen | 500 units | EUR 859.2 |
×
The genetic range was average (π = 0.00265 and Hd = 0.424) and regarded appropriated for this breeding inhabitants of pacu. Our outcomes present help for the genetic range upkeep and mtDNA traceability of pacu business broodstocks.
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