• June 23, 2021
H 2 O 2 enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage

H 2 O 2 enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage

Most cancers is likely one of the ailments that threatens human well being and is a number one reason behind mortality worldwide. Excessive ranges of reactive oxygen species (ROS) have been noticed in most cancers tissues in contrast with regular tissues in vivo, and it’s not but recognized how this influences chemotherapeutic drug motion. Cationic porphyrin 5,10,15,20-tetra-(N-methyl-4-pyridyl) porphyrin (TMPyP4) is a photosensitizer utilized in photodynamic remedy (PDT) and a telomerase inhibitor used within the remedy of telomerase-positive most cancers.
Right here, we investigated the anticancer exercise of TMPyP4 in A549 and PANC cells cultured in H2O2. The outcomes confirmed that in comparison with TMPyP4 alone, the mix of TMPyP4 and H2O2 exhibited sensitization results on cell viability and colony formation inhibition and apoptosis in A549 and PANC cells, however had no impact in human regular MIHA cells.
Mechanistically, the mix of TMPyP4 and H2O2 prompts excessive ROS and mitochondrial membrane potential in A549 and PANC cells, leading to intense DNA harm and DNA harm responses. Consequently, in comparison with TMPyP4 alone, TMPyP4 and H2O2 mixed remedy upregulates the expression of BAX, cleaved caspase 3, and p-JNK and downregulates the expression of Bcl-2 in A549 and PANC cells. Taken collectively, these knowledge prompt that H2O2 enhanced the anticancer exercise of TMPyP4-mediated ROS-dependent DNA harm and associated apoptotic protein regulation, revealing that the excessive ROS tumor microenvironment performs an vital position in chemotherapeutic drug motion.

Survival of an launched ectomycorrhizal Laccaria bicolor pressure in a European forest plantation monitored by mitochondrial ribosomal DNA evaluation

Mitochondrial and nuclear genes have totally different inheritance, thus research of fungal populations ought to use each mitochondrial and nuclear markers. Utilizing nuclear markers, the S238N pressure of the ectomycorrhizal basidiomycete Laccaria bicolor ((Maire) Orton) has been beforehand proven to persist for a minimum of 10 yr after outplanting in a plantation of Douglas fir (Pseudotsuga menziesii (Mir.) Franco) inoculated with this pressure. Within the current research, we’ve got sampled 539 sporophores of Laccaria spp. from this plantation, a few of which had the S238N nuclear genotype, to review mitochondrial DNA polymorphism and persistence of the inoculated S238N mitochondrial genome.
Size polymorphism in fragments of the big subunit of mitochondrial ribosomal DNA (LrDNA) allowed distinction of the haplotypes current within the plantation on the species stage. As well as, heteroduplex evaluation and sequencing revealed intraspecific polymorphism of LrDNA among the many L. bicolor sporophores and enabled particular identification of S238N LrDNA. This haplotype was solely retained in sporophores carrying the S238N nuclear genome, confirming the survival of this launched pressure in a pure inhabitants.

Bioallethrin enhances technology of ROS, damages DNA, impairs the redox system and causes mitochondrial dysfunction in human lymphocytes

Bioallethrin is an artificial pesticide that’s extensively used to manage insect pests. The broad use of bioallethrin has resulted in inevitable human publicity. On this research we report the impact of various concentrations of bioallethrin (10 to 200 µM, 2 h at 37 °C) on human lymphocytes underneath in vitro circumstances. Bioallethrin remedy resulted in lack of cell viability (> 30% at 200 µM bioallethrin). Oxidative stress markers like lipid peroxidation and protein oxidation have been considerably elevated accompanied by decrease ratio of decreased to oxidized glutathione.
H 2 O 2 enhances the anticancer activity of TMPyP4 by ROS-mediated mitochondrial dysfunction and DNA damage
Enhanced ROS technology was noticed by way of fluorescence spectroscopy and microscopy. Bioallethrin-induced oxidative stress additionally compromised the antioxidant defence because it decreased antioxidant capability of cells and inhibited main antioxidant enzymes. Biomolecular modifications and systemic toxicity by bioallethrin resulted in plasma membrane harm with mitochondrial depolarization.
Comet assay confirmed nuclear DNA fragmentation and strand scission with vital enhance in tail size and olive tail second. Apoptosis and necrosis of cells was confirmed by way of acridine orange/ethidium bromide twin staining and visualization underneath fluorescence microscope. Thus, bioallethrin causes oxidative harm and compromises the antioxidant system resulting in DNA harm, mobile and organelle toxicity, leading to apoptosis and necrosis of human lymphocytes.

Unearthing Neanderthal inhabitants historical past utilizing nuclear and mitochondrial DNA from cave sediments

Bones and enamel are vital sources of Pleistocene hominin DNA, however are hardly ever recovered at archaeological websites. Mitochondrial DNA has been retrieved from cave sediments, however offers restricted worth for learning inhabitants relationships. We due to this fact developed strategies for the enrichment and evaluation of nuclear DNA from sediments, and utilized them to cave deposits in western Europe and southern Siberia dated to between roughly 200,000 and 50,000 years in the past.
We detect a inhabitants substitute in northern Spain roughly 100,000 years in the past, accompanied by a turnover of mitochondrial DNA. We additionally establish two radiation occasions in Neanderthal historical past through the early a part of the Late Pleistocene. Our work lays the bottom for learning the inhabitants historical past of historical hominins from hint quantities of nuclear DNA in sediments.

Mitochondrial DNA mutations contribute to excessive altitude pulmonary edema by way of elevated oxidative stress and metabolic reprogramming throughout hypobaric hypoxia

Excessive altitude pulmonary edema (HAPE) is skilled by non-acclimatized sea stage people on publicity to excessive altitude hypoxic circumstances. Obtainable proof means that genetic elements and perturbed mitochondrial redox standing could play an vital position in HAPE pathophysiology. Nevertheless, the exact mechanism has not been absolutely understood.
Within the current research, sequencing of mitochondrial DNA (mtDNA) from HAPE topics and acclimatized controls was carried out to establish pathogenic mutations and to find out their position in HAPE. Hypobaric hypoxia induced oxidative stress and metabolic alterations have been additionally assessed in HAPE topics. mtDNA copy quantity, mitochondrial oxidative phosphorylation (mtOXPHOS) exercise, mitochondrial biogenesis have been measured to find out mitochondrial features.
The information revealed that the mutations in Advanced I genes impacts the secondary construction of protein in HAPE topics. Additional, elevated oxidative stress throughout hypobaric hypoxia, decreased mitochondrial biogenesis and mtOXPHOS exercise induced metabolic reprogramming which may contribute to mitochondrial dysfunctions in HAPE people.

Recombinant Taq Dna Polymerase

27079806 EACH
EUR 607.62

Taq DNA Polymerase (Recombinant)

22060707-1 1,000 Unit(s)
EUR 137.27

Taq DNA Polymerase (Recombinant)

22060707-2 1500 Unit(s)
EUR 182.1

Taq DNA Polymerase (Recombinant)

22060707-3 5000 Unit(s)
EUR 465.77

Taq DNA Polymerase (Recombinant)

22060707-4 10 KU
EUR 840.96

Recombinant Pfu DNA Polymerase

7-03322 100U Ask for price

Recombinant Pfu DNA Polymerase

7-03323 500U Ask for price

Recombinant Pfu DNA Polymerase

7-03324 2500U Ask for price

Recombinant Taq DNA Polymerase

7-03634 1,000U Ask for price

Recombinant Taq DNA Polymerase

7-03635 3,000U Ask for price

Recombinant Taq DNA Polymerase

7-03636 10,000U Ask for price

Pfu DNA Polymerase (Recombinant)

abx074017-100U 100 U
EUR 393.6

Pfu DNA Polymerase (Recombinant)

abx074017-2500U 2500 U
EUR 1528.8

Pfu DNA Polymerase (Recombinant)

abx074017-500U 500 U
EUR 526.8

Taq DNA Polymerase (Recombinant)

abx073521-10000U 10000 U
EUR 710.4

Taq DNA Polymerase (Recombinant)

abx073521-1000U 1000 U
EUR 276

Taq DNA Polymerase (Recombinant)

abx073521-3000U 3000 U
EUR 393.6

Taq DNA Polymerase Recombinant

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DNA Topoisomerase-I (Recombinant)

20-abx073616
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  • 5 ug

Recombinant (E.Coli) T4 DNA Ligase

RP-374 20 KU
EUR 196.8

Recombinant human DNA-directed DNA/RNA polymerase mu

P2815 100ug Ask for price
Description: Recombinant protein for human DNA-directed DNA/RNA polymerase mu

Recombinant Taq Dna Polymerase - EACH

27079804 EACH
EUR 132.3

Recombinant Taq Plus DNA Polymerase

7-03631 250U Ask for price

Recombinant Taq Plus DNA Polymerase

7-03632 750U Ask for price

Recombinant Taq Plus DNA Polymerase

7-03633 2,500U Ask for price

Taq Plus DNA Polymerase (Recombinant)

abx073522-2500U 2.500 U
EUR 710.4

Taq Plus DNA Polymerase (Recombinant)

abx073522-250U 250 U
EUR 276

Taq Plus DNA Polymerase (Recombinant)

abx073522-750U 750 U
EUR 393.6

Recombinant (E.Coli) Taq DNA Polymerase

RP-394 1000 IU
EUR 196.8

Taq Plus DNA Polymerase Recombinant

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Recombinant Human DNA-directed DNA/RNA polymerase mu (POLM)

CSB-YP889065HU 6730 mg Ask for price

Recombinant Human DNA-directed DNA/RNA polymerase mu (POLM)

CSB-EP889065HU 4769 mg Ask for price

Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM)

AP77539 each Ask for price

Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM)

AP77602 1mg
EUR 2826

Recombinant Human DNA-directed DNA/RNA polymerase mu(POLM)

AP77996 each Ask for price

Recombinant Human DNA-directed DNA/RNA polymerase mu (POLM)

CSB-BP889065HU 277 mg Ask for price

Recombinant Human DNA-directed DNA/RNA polymerase mu (POLM)

RPC23722-100ug 100ug
EUR 572

Recombinant Human DNA-directed DNA/RNA polymerase mu (POLM)

RPC23722-1mg 1mg
EUR 2884.7

Recombinant Human DNA-directed DNA/RNA polymerase mu (POLM)

RPC23722-20ug 20ug
EUR 353.4

Recombinant Human DNA-directed DNA/RNA polymerase mu (POLM)

RPC20704-100ug 100ug
EUR 1463

Recombinant Human DNA-directed DNA/RNA polymerase mu (POLM)

RPC20704-20ug 20ug
EUR 580.8

Recombinant Uracil DNA Glycosylase (UNG)

RPU51901-100ug 100ug
EUR 504.9

Recombinant Uracil DNA Glycosylase (UNG)

RPU51901-1mg 1mg
EUR 2238.6

Recombinant Uracil DNA Glycosylase (UNG)

RPU51901-50ug 50ug
EUR 405.9

Recombinant Uracil DNA Glycosylase (UNG)

RPG917Hu01 10ug
EUR 164

Recombinant Uracil DNA Glycosylase (UNG)

4-RPG917Hu01
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Description: Recombinant Human Uracil DNA Glycosylase expressed in: E.coli

Human DNA Topoisomerase-I (Recombinant)

22060306-1 5 µg
EUR 146.42

Recombinant Human DNA Topoisomerase-I

7-03658 5µg Ask for price

Recombinant Human DNA Topoisomerase-I

7-03659 20µg Ask for price

Recombinant Human DNA Topoisomerase-I

7-03660 1mg Ask for price

DNA Polymerase beta Recombinant Protein

91-139 0.05 mg
EUR 651.3
Description: Human DNA polymerase beta is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. The activity cannot be affected by Aphidicolin, which is an inhibitor of DNA polymerase beta .

Uracil DNA Glycosylase E.Coli Recombinant

rAP-1141 Inquiry Ask for price

DNA Topoisomerase-I Human Recombinant

rAP-1220 Inquiry Ask for price

E.Coli Adenine DNA Glycosylase (Recombinant)

20-abx074009
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Polymerase (DNA directed), beta (Recombinant)

20-abx073237
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  • 1 mg
  • 20 ug
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Adenine DNA Glycosylase E.Coli Recombinant

rAP-1139 Inquiry Ask for price

Recombinant Human DNA ligase 1 (LIG1)

CSB-EP012930HU 1617 mg Ask for price

Recombinant Human DNA ligase 1(LIG1)

AP70504 1mg
EUR 1978

DNA-PKcs recombinant monoclonal antibody

A5876 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human DNA-PKcs for WB, IHC,ELISA

8-Oxoguanine DNA Glycosylase (Recombinant)

20-abx073274
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  • 1 mg
  • 25 ug
  • 5 ug

Polymerase (DNA directed), lambda (Recombinant)

20-abx073724
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  • 10 ug
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  • 2 µg

Recombinant DNA Methyltransferase 1 (DNMT1)

RPJ244Hu01 10ug
EUR 172

Recombinant DNA Methyltransferase 1 (DNMT1)

4-RPJ244Hu01
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Description: Recombinant Human DNA Methyltransferase 1 expressed in: E.coli

Recombinant DNA Methyltransferase 1 (DNMT1)

RPJ244Mu01 10ug
EUR 140

Recombinant DNA Methyltransferase 1 (DNMT1)

RPJ244Mu02 10ug
EUR 140

Recombinant DNA Methyltransferase 1 (DNMT1)

RPU41218-100ug 100ug
EUR 530.2

Recombinant DNA Methyltransferase 1 (DNMT1)

RPU41218-1mg 1mg
EUR 2347.8

Recombinant DNA Methyltransferase 1 (DNMT1)

RPU41218-50ug 50ug
EUR 425.7

Recombinant DNA Methyltransferase 3A (DNMT3A)

RPJ245Hu01 10ug
EUR 140

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPJ246Hu01 10ug
EUR 140

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPJ246Mu01 10ug
EUR 172

Recombinant DNA Methyltransferase 3B (DNMT3B)

4-RPJ246Mu01
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Description: Recombinant Mouse DNA Methyltransferase 3B expressed in: E.coli

Recombinant DNA Methyltransferase 3A (DNMT3A)

RPU59419-100ug 100ug
EUR 470.4

Recombinant DNA Methyltransferase 3A (DNMT3A)

RPU59419-1mg 1mg
EUR 2047.5

Recombinant DNA Methyltransferase 3A (DNMT3A)

RPU59419-50ug 50ug
EUR 336

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPU57666-100ug 100ug
EUR 470.4

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPU57666-1mg 1mg
EUR 2184

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPU57666-50ug 50ug
EUR 385

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPU57667-100ug 100ug
EUR 470.4

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPU57667-1mg 1mg
EUR 2184

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPU57667-50ug 50ug
EUR 385

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPU52741-100ug 100ug
EUR 530.2

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPU52741-1mg 1mg
EUR 2347.8

Recombinant DNA Methyltransferase 3B (DNMT3B)

RPU52741-50ug 50ug
EUR 425.7

DNA Topoisomerase-I 70 kDa (Recombinant)

20-abx073615
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  • 1 mg
  • 20 ug
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Recombinant (E.Coli) Taq Plus DNA Polymerase

RP-395 250 U
EUR 196.8

Recombinant DNA-binding protein fis (fis)

CSB-YP358868SWW 10100 mg Ask for price

Recombinant human DNA repair protein REV1

P2230 100ug Ask for price
Description: Recombinant protein for human DNA repair protein REV1

TAR DNA Binding Protein Human Recombinant

rAP-4928 Inquiry Ask for price

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU41219-100ug 100ug
EUR 665.5

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU41219-1mg 1mg
EUR 2948.4

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU41219-50ug 50ug
EUR 534.6

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU41220-100ug 100ug
EUR 665.5

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU41220-1mg 1mg
EUR 2948.4

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU41220-50ug 50ug
EUR 534.6

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU54001-100ug 100ug
EUR 566.5

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU54001-1mg 1mg
EUR 2511.6

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU54001-50ug 50ug
EUR 455.4

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU56270-100ug 100ug
EUR 573.1

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU56270-1mg 1mg
EUR 2538.9

Recombinant DNA Repair Protein RAD50 (RAD50)

RPU56270-50ug 50ug
EUR 460.9

Recombinant DNA Repair Protein RAD50 (RAD50)

RPK111Hu01 10ug
EUR 216

Recombinant DNA Repair Protein RAD50 (RAD50)

4-RPK111Hu01
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Description: Recombinant Human DNA Repair Protein RAD50 expressed in: E.coli

Recombinant DNA Repair Protein RAD50 (RAD50)

RPK111Hu02 10ug
EUR 216

Recombinant DNA Repair Protein RAD50 (RAD50)

4-RPK111Hu02
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Description: Recombinant Human DNA Repair Protein RAD50 expressed in: E.coli

Recombinant DNA Repair Protein RAD50 (RAD50)

RPK111Mu01 10ug
EUR 184

Recombinant DNA Repair Protein RAD50 (RAD50)

4-RPK111Mu01
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Description: Recombinant Mouse DNA Repair Protein RAD50 expressed in: E.coli

Recombinant DNA Repair Protein RAD50 (RAD50)

RPK111Ra01 10ug
EUR 188

OPPA00808-20KIU - T4 DNA Ligase Recombinant

OPPA00808-20KIU 20,000IU
EUR 81

Recombinant Escherichia coli DNA ligase (ligA)

CSB-EP322745ENV 2850 mg Ask for price

Recombinant Escherichia coli DNA ligase(ligA)

AP71013 1mg
EUR 2826

Recombinant human DNA-binding protein RFX2

P2855 100ug Ask for price
Description: Recombinant protein for human DNA-binding protein RFX2

Recombinant Human DNA Topoisomerase-I 70kDa

7-03661 5µg Ask for price

Recombinant Human DNA Topoisomerase-I 70kDa

7-03662 20µg Ask for price

Recombinant Human DNA Topoisomerase-I 70kDa

7-03663 1mg Ask for price

DNA Ligase IV recombinant monoclonal antibody

A5820 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human DNA Ligase IV for WB, IHC, IF,ELISA

Recombinant DNA expression in Pichia pastoris

HESAP-1002-10G 10G
EUR 2250

DNA Topoisomerase-I 70kDa Recombinant Human

rAP-1208 Inquiry Ask for price

Recombinant human DNA-binding protein RFXANK

P2771 100ug Ask for price
Description: Recombinant protein for human DNA-binding protein RFXANK

Polymerase (DNA directed), Beta Human Recombinant

rAP-1060 Inquiry Ask for price

Recombinant Human DNA nucleotidylexotransferase (DNTT)

CSB-EP007088HU 1036 mg Ask for price

Recombinant Human DNA nucleotidylexotransferase(DNTT)

AP70241 1mg
EUR 1978

Recombinant Human DNA nucleotidylexotransferase (DNTT)

RPC21219-100ug 100ug
EUR 460.9

Recombinant Human DNA nucleotidylexotransferase (DNTT)

RPC21219-1mg 1mg
EUR 2237.8

Recombinant Human DNA nucleotidylexotransferase (DNTT)

RPC21219-20ug 20ug
EUR 258.7

Recombinant Human 8-Oxoguanine DNA Glycosylase

7-03277 5µg Ask for price

Recombinant Human 8-Oxoguanine DNA Glycosylase

7-03278 20µg Ask for price

Recombinant Human 8-Oxoguanine DNA Glycosylase

7-03279 1mg Ask for price

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPH625Hu01 10ug
EUR 169

Recombinant N-Methylpurine DNA Glycosylase (MPG)

4-RPH625Hu01
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Description: Recombinant Human N-Methylpurine DNA Glycosylase expressed in: E.coli

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPH625Mu01 10ug
EUR 176

Recombinant N-Methylpurine DNA Glycosylase (MPG)

4-RPH625Mu01
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Description: Recombinant Mouse N-Methylpurine DNA Glycosylase expressed in: E.coli

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPH625Ra01 10ug
EUR 188

Recombinant N-Methylpurine DNA Glycosylase (MPG)

4-RPH625Ra01
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Description: Recombinant Rat N-Methylpurine DNA Glycosylase expressed in: E.coli

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPU43074-100ug 100ug
EUR 520.3

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPU43074-1mg 1mg
EUR 2303.6

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPU43074-50ug 50ug
EUR 418

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPU43075-100ug 100ug
EUR 542.3

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPU43075-1mg 1mg
EUR 2402.4

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPU43075-50ug 50ug
EUR 435.6

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPU43076-100ug 100ug
EUR 578.6

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPU43076-1mg 1mg
EUR 2566.2

Recombinant N-Methylpurine DNA Glycosylase (MPG)

RPU43076-50ug 50ug
EUR 465.3

8-Oxoguanine DNA Glycosylase Mouse Recombinant

rAP-1132 Inquiry Ask for price

8-Oxoguanine DNA Glycosylase Human Recombinant

rAP-1134 Inquiry Ask for price

Polymerase (DNA directed), Lambda Human Recombinant

rAP-1590 Inquiry Ask for price

Recombinant DNA-binding protein H-NS(hns)

AP74001 1mg
EUR 2826

Recombinant Human DNA Polymerase β (C-6His)

AP74892 1mg
EUR 3209

Recombinant Human DNA Polymerase β (C-6His)

C159-10ug 10ug
EUR 187.2
Description: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8.

Recombinant Human DNA Polymerase β (C-6His)

C159-1mg 1mg
EUR 2739.6
Description: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8.

Recombinant Human DNA Polymerase β (C-6His)

C159-500ug 500ug
EUR 1935.6
Description: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8.

Recombinant Human DNA Polymerase β (C-6His)

C159-50ug 50ug
EUR 442.8
Description: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8.

Recombinant ATP Dependent DNA ligase I (LIG1)

RPU54179-100ug 100ug
EUR 578.6

Recombinant ATP Dependent DNA ligase I (LIG1)

RPU54179-1mg 1mg
EUR 2566.2

Recombinant ATP Dependent DNA ligase I (LIG1)

RPU54179-50ug 50ug
EUR 465.3

Recombinant ATP Dependent DNA ligase I (LIG1)

RPU54517-100ug 100ug
EUR 603.9

Recombinant ATP Dependent DNA ligase I (LIG1)

RPU54517-1mg 1mg
EUR 2675.4

Recombinant ATP Dependent DNA ligase I (LIG1)

RPU54517-50ug 50ug
EUR 485.1

Recombinant ATP Dependent DNA ligase I (LIG1)

RPB269Hu01 10ug
EUR 188

Recombinant ATP Dependent DNA ligase I (LIG1)

4-RPB269Hu01
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  • 5 mg
Description: Recombinant Human ATP Dependent DNA ligase I expressed in: E.coli

Recombinant ATP Dependent DNA ligase I (LIG1)

RPB269Ra01 10ug
EUR 196

Recombinant ATP Dependent DNA ligase I (LIG1)

4-RPB269Ra01
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  • 100 ug
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Description: Recombinant Rat ATP Dependent DNA ligase I expressed in: E.coli

Recombinant Single-stranded DNA Binding Protein

AP60509 500ug
EUR 183

Recombinant Tyrosyl DNA Phosphodiesterase 1 (TDP1)

RPC785Hu01 10ug
EUR 140

Recombinant Tyrosyl DNA Phosphodiesterase 1 (TDP1)

RPC785Mu01 10ug
EUR 132

Recombinant Tyrosyl DNA Phosphodiesterase 1 (TDP1)

4-RPC785Mu01
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Tyrosyl DNA Phosphodiesterase 1 expressed in: E.coli
Haplogroup evaluation means that mtDNA haplogroup H2a2a1 has potential contribution within the pathobiology of HAPE in lowlanders. This research suggests contribution of altered mitochondrial features in HAPE susceptibility.

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